Contrast media-induced encephalopathy in Chinese patients
- PDF / 169,620 Bytes
- 1 Pages / 595.245 x 841.846 pts (A4) Page_size
- 3 Downloads / 199 Views
1
Contrast media-induced encephalopathy in Chinese patients Contrast media-induced encephalopathy (CIE) is rare but appears to be more common after iopromide injection than after ioversol injection, according to findings of a Chinese study published in Clinical Neuropharmacology. Data from two regional hospitals in China were used to investigate the incidence of iopromide-related and ioversolrelated CIE in patients undergoing neurosurgery. The incidence of CIE was 0.38% overall, and was significantly higher after iopromide injection than after ioversol injection (0.95% vs 0.26%; p=0.029). Five cases of CIE were reported after use of iopromide (n=526) and seven cases were reported after use of ioversol (2646). Acute cerebral infarction was found to be an independent risk factor for CIE (odds ratio 4.024: 95% CI 1.137, 14.236; p=0.031). CIE occurred within five minutes after injection of the contrast media in some patients. The most frequent symptoms of CIE were delirium, which was more frequent after iopromide use than after ioversal use (100% vs 57%), and vision disorders, which were more frequent after ioversol use than after iopromide use (71% vs 20%). "Compared with ioversol, using iopromide led to a higher incidence of CIE," concluded the investigators. "The characteristics of CIE were different for the 2 contrast media," they said, but the different effects need confirmation due to the small number of cases in this study. Zhang G, et al. Contrast-Induced Encephalopathy Resulting From Use of Ioversol and Iopromide. Clinical Neuropharmacology : 30 Dec 2019. Available from: URL: http:// 803446552 doi.org/10.1097/WNF.0000000000000374
0114-9954/20/1787-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved
Reactions 18 Jan 2020 No. 1787
Data Loading...
