Correction to: Plasma free amino acid profiling as metabolomic diagnostic and prognostic biomarker in paediatric cancer

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CORRECTION

Correction to: Plasma free amino acid profiling as metabolomic diagnostic and prognostic biomarker in paediatric cancer patients: a follow‑up study Anna Synakiewicz1 · Anna Stanislawska‑Sachadyn2 · Malgorzata Sawicka‑Zukowska3 · Grazyna Galezowska4 · Joanna Ratajczyk4 · Anna Owczarzak5 · Malgorzata Skuza6 · Lidia Wolska4 · Teresa Stachowicz‑Stencel1 

© The Author(s) 2020

Correction to: Amino Acids https​://doi.org/10.1007/s0072​6-020-02910​-8

The correct Table 1 is given in this correction. The original article has been updated.

In the original publication of the article, Table 1 has been published with an error. The data in the columns is not placed under its headings.

The original article can be found online at https​://doi.org/10.1007/ s0072​6-020-02910​-8. * Teresa Stachowicz‑Stencel [email protected] 1

2





Department of Pediatrics, Hematology and Oncology, Medical University of Gdansk, 7 Debinki Street, 80‑211, Gdansk, Poland Department of Molecular Biotechnology and Microbiology, Gdansk University of Technology, Gdansk, Poland

3



Department of Pediatric Oncology and Hematology, Medical University of Bialystok, Bialystok, Poland

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Department of Environmental Toxicology, Medical University of Gdansk, Gdansk, Poland

5



Department of Clinical Nutrition, Medical University of Gdansk, Gdansk, Poland

6



Diagnostic Imaging Department, The Polish Red Cross Maritime Hospital, Gdynia, Poland

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A. Synakiewicz et al.

Table 1  Characteristics of study population Age at blood collection

All

Cases time 1 (diagnosis)

Cases time 3 (post-treatment), Healthy controls follow-up

Median (q1– q3), N

Mean, StDev

Median (q1– q3), N

8 (2–16), 39

9.14, 6.45

Median (q1– q3), N

Mean, StDev

8.7 (3.5–16.7), 9.99, 6.52 39 15.2 (6.5–17.1), 12.73, 5.41 18 5.3 (2.4–13.6), 7.65, 6.59 21

13 (9–16), 33

11.91, 4.87

Hematologic 14 (6–16), 18 malignancies Solid tumours 4 (2–12), 21

6.83, 6.59

Amino ­acida

Mean, StDev

Median (q1– q3), N

Mean, StDev

Median (q1– q3), N

Mean, StDev

P ­valueb Cases before vs. after treatment

102.1 (17.6– 123.4), 39 112.1 (82– 169.9), 39 79.5 (33.2– 104.1), 38 357.4 (269.8– 473.2), 39 151.3 (70.3– 213.3), 39 Histidine (His) 89.4 (47.8– 150.9), 39 164.6 (136.8– Citrulline/ glycine (Cit/ 208.7), 39 Gly) Arginine (Arg) 97.85 (67.7– 151.3), 38 Threonine (Thr)142.5 (90.6– 194.3), 39 Taurine (Tau) 65.3 (44.8– 147.7), 38 Alanine (Ala) 175.5 (96.1– 323.4), 39 Tyrosine (Tyr) 173.0 (126.2– 223.7), 39 GABA 74.6 (37.9– 86.6), 39 Tryptophan 104.3 (25.9– (Trp) 164.8), 39 Methionine 44.1 (20.2– (Met) 94.1), 39 Valine (Val) 202.8 (138.3– 248.0), 39

82.8, 82.2

103 (4.3– 119.1), 39 78.5 (60.7– 108.2), 39 94.65 (15.1– 102.1), 38 306.0 (201.7– 414.2), 39 150.3 (59.1– 201), 39 71.2 (42.0– 15.0), 39 175.6 (148.8– 569.6), 39

73.2, 59.7

22.9 (15.8– 32.05), 32 86.8 (69.1– 123.8), 33 21.5 (14.8– 29.6), 33 741.2 (375.1– 1106.4), 33 78.9 (55.2– 101.5), 33 127.5 (77.8– 168.5), 33 134.4 (80.1– 168.6), 33

24.6, 16.1

0.5553

0.1139

96.5, 40.7

0.004

0.4185