Cortex Mori radicis Sangbaipi
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Pharmacopoeia of the People’s Republic of China, English Edition, 2000/2005
Of¿cial drug(1):
White Mulberry Root-bark is the dried root bark of Morus alba L. – Moraceae – The root is collected in late autumn while leaf falling off and in early spring before germination, removed from the yellowishbrown coarse bark, cut longitudinally. The root bark is stripped off and dried in the sun.
Origin(2):
China, Indochina, Japan, Philippines
Descriptions of the drug(1):
Quilled, channelled or Àat pieced, twisted, varying in length and width, 1 – 4 mm thick. Outer surface white or pale yellowishwhite, relatively even, some with orange-yellow or brownishyellow remains of scaly bark; inner surface yellowish-white or greyish-yellow, with ¿ne longitudinal striations. Texture light and tenacious, strongly ¿brous, uneasily broken, but easily stripped longitudinally, dusting on stripping. Odour, slight; taste, slightly sweet.
Pretreatment of the raw drug(1):
The drug is washed clean, softened brieÀy, cut into slivers and dried. Cortex Mori (stir-baked with honey) (= Misangbaipi): The re¿ned honey should be diluted at ¿rst with a quantity of boiling water. Then it is added to the clean slivers and mixed well in a closed vessel until they are infused thoroughly. They are roasted in a pot with gentle heat until it is no more sticky to ¿ngers, taken out and cooled. 25 kg of re¿ned honey is used for each 100 kg of clean crude drug.
Medicinal use(2,3):
Hypertension, asthma, cough, inÀammations
H. Wagner et al. (eds.), Chromatographic Fingerprint Analysis of Herbal Medicines © Springer-Verlag/Wien 2011
535
Cortex Mori radicis – Sangbaipi
Effects and indications of Cortex Mori according to Traditional Chinese Medicine(1,4) Taste:
sweet
Temperature:
cold
Channels entered:
orbis pulmonalis, orbis hepaticus, orbis lienalis
Effects (functions):
removes heat from the lung, relieves asthma, decongestant and induces diuresis
Symptoms and indications:
cough and asthma caused by heat in the lung; anasarca with oliguria, fever
Main constituents:
- prenylÀavone- and Àavanone-compounds: mulberrin (kuwanone C)(5), cyclomulberrin(5), mulberrochromene (morusin)(5), cyclomulberrochromene (cyclomorusin)(5), mulberranol(5), oxydihydromorusin (morusinol)(5), kuwanon A(5), B(5), D – F(5), G (albanin F, moracenin B)(5), H (albanin G, moracenin A)(5), I – T(5), V – Z(5), kuwanol A(5), B(5), sanggenone A – Q(5), moracenin C(5), D(5), mulberrofuran A – Q(5), albanol B(5), albafuran A – C(5), mulberroside A(6), mulberroside C(7), moralbanone(7), eudraÀavone B hydroperoxide(7), leachianone G(7), alpha-acetyl-amyrin(7), cudraÀavone B(8), C(8) - phenylbenzofurane derivatives: moracin A – M(5), dimoracin(5) - other phenolic compounds: umbelliferone(5), scopoletin(5), ethyl 2,4-dihydroxybenzoate(5), 5,7-dihydroxychromone(5), oxyresveratrol(6), 5,7-dihydroxycoumarin-7-methylether(8) - alkaloids: moranoline (piperidine alkaloid)(5), 1,4-dideoxy-1,4-imino-Dribitol (pyrrolidine alkaloid)(9), (2R, 3R, 4R)-2-hydroxymethyl3,4-dihydroxypyrrolidine-N-pr
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