Cross-frequency and iso-frequency estimation of functional corticomuscular coupling after stroke
- PDF / 2,138,579 Bytes
- 13 Pages / 595.276 x 790.866 pts Page_size
- 99 Downloads / 161 Views
(0123456789().,-volV)(0123456789(). ,- volV)
RESEARCH ARTICLE
Cross-frequency and iso-frequency estimation of functional corticomuscular coupling after stroke Ping Xie1 • Xiaohui Pang1 • Shengcui Cheng1 • Yuanyuan Zhang1 • Yinan Yang2 • Xiaoli Li3 Xiaoling Chen1
•
Received: 29 January 2020 / Revised: 21 July 2020 / Accepted: 7 September 2020 Ó Springer Nature B.V. 2020
Abstract Functional corticomuscular coupling (FCMC) between the brain and muscles has been used for motor function assessment after stroke. Two types, iso-frequency coupling (IFC) and cross-frequency coupling (CFC), are existed in sensory-motor system for healthy people. However, in stroke, only a few studies focused on IFC between electroencephalogram (EEG) and electromyogram (EMG) signals, and no CFC studies have been found. Considering the intrinsic complexity and rhythmicity of the biological system, we first used the wavelet package transformation (WPT) to decompose the EEG and EMG signals into several subsignals with different frequency bands, and then applied transfer entropy (TE) to analyze the IFC and CFC relationship between each pair-wise subsignal. In this study, eight stroke patients and eight healthy people were enrolled. Results showed that both IFC and CFC still existed in stroke patients (EEG ? EMG: 1:1, 3:2, 2:1; EMG ? EEG: 1:1, 2:1, 2:3, 3:1). Compared with the stroke-unaffected side and healthy controls, the stroke-affected side yielded lower alpha, beta and gamma synchronization (IFC: beta; CFC: alpha, beta and gamma). Further analysis indicated that stroke patients yielded no significant difference of the FCMC between EEG ? EMG and EMG ? EEG directions. Our study indicated that alpha and beta bands were essential to concentrating and maintaining the motor capacities, and provided a new insight in understanding the propagation and function in the sensory-motor system. Keywords Cross-frequency coupling Functional corticomuscular coupling Iso-frequency coupling Stroke
Introduction Motor dysfunction is a major consequence after stroke (De Oliveira et al. 2020; Rathore et al. 2002) and it is generally believed that the loss of motor ability is caused by impairments in neural network controling movement (Chen et al. 2018). Functional corticomuscular coupling (FCMC) & Ping Xie [email protected] & Xiaoling Chen [email protected] 1
Key Lab of Measurement Technology and Instrumentation of Hebei Province, Yanshan University, Qinhuangdao, Hebei, China
2
Department of Rehabilitation Medicine, First Hospital of Qinhuangdao, Hebei, China
3
State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China
between the motor cortex and the effector muscles, as a neurophysiological measure, has been used for motor function after stroke (Fang et al. 2009; Meng et al. 2009; Mima et al. 2001b). It has been considered as a key to signal transmission between functionally related motor cortex and the effector muscles through direct and indirect pathways (Grosse et al. 2003; Jang and Seo 2014; Van Wij
Data Loading...
