Day-to-day repeatability of the results of the finger-toe-plot analysis
Non-invasive arterial pulse wave (PW) measurement provides valuable information on the vascular health. The aim of the study is to characterize the between-visit or day-to-day repeatability of combined finger and toe photoplethysmographic (PPG) signal ana
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BioMediTech Institute and Faculty of Biomedical Sciences and Engineering, Tampere University of Technology, Tampere, Finland Tampere University Hospital, Finland, and Surgery, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Abstract— Non-invasive arterial pulse wave (PW) measurement provides valuable information on the vascular health. The aim of the study is to characterize the between-visit or day-today repeatability of combined finger and toe photoplethysmographic (PPG) signal analysis method called finger-toe plot (FTplot) and compare it with the repeatability of other methods proposed for vascular characterization. Ten 22–36-year-old subjects were examined on 3 different days in order to find out the day-to-day repeatability of the results. The repeatability of the extracted parameters was analyzed by means of intra-class correlation coefficients (ICC) and free-marginal multirater κ agreement. ICCs varied widely from below 0.2 to almost 0.9, but κ coefficients higher than 0.7 were achieved for most of the results. Based on the presented results, the FT-plot analysis has at least sufficient day-to-day repeatability. However, further studies with real patients and different stages of cardiovascular diseases are required for confirming the findings. Keywords— Atherosclerosis, Photoplethysmography
I. I NTRODUCTION Aging and unhealthy lifestyle cause stiffening and thickening of the arterial walls. The stiffening due to the aging is classically known as arteriosclerosis and thickening, stenosis or occlusion of the arteries due to accumulation of cholesterol is known as atherosclerosis. The markers of these conditions are often concomitantly present and are considered as a continuum of degenerative changes and indicators of increased risk for severe cardiovascular events. Methods for estimating atherosclerotic changes include the angiograms and the measurement of carotid-femoral pulse wave (PW) velocity or the intima media thickness of the carotid artery by using ultrasonic transducers [1, 2], but they require either a skilled operator or expensive equipment. A standard method for screening the occlusive atherosclerosis is ankle-to-brachial pressure index (ABI), but its performance decreases when there are also type 2 diabetic changes present [3]. To detect especially subclinical atherosclerosis, there is a growing need for alternative methods for measuring the vascular system. Many arterial PW measurement based noninvasive methods have been proposed for characterizing the vascular status, as e.g. in [4, 5]. The propagation of the waves and their reflections and thus the shape of the observed PWs and parameters derived from them depends e.g. on arterial wall properties, fluidic properties of the blood, blood pres© Springer Nature Singapore Pte Ltd. 2018 H. Eskola et al. (eds.), EMBEC & NBC 2017, IFMBE Proceedings 65, DOI: 10.1007/978-981-10-5122-7_134
sure and vascular resistance. Due to the complexity of the arterial tree, there are several theories about the origin of the wave re
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