Decreased COPD prevalence in Sweden after decades of decrease in smoking
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RESEARCH
Decreased COPD prevalence in Sweden after decades of decrease in smoking Helena Backman1* , Lowie Vanfleteren2, Anne Lindberg3, Linda Ekerljung4, Caroline Stridsman3,6, Malin Axelsson5, Ulf Nilsson3, Bright I. Nwaru4,8, Sami Sawalha3, Berne Eriksson4,7, Linnea Hedman1,6, Madeleine Rådinger4, Sven‑Arne Jansson1, Anders Ullman2, Hannu Kankaanranta4,9,10, Jan Lötvall4, Eva Rönmark1 and Bo Lundbäck4
Abstract Background: COPD has increased in prevalence worldwide over several decades until the first decade after the mil‑ lennium shift. Evidence from a few recent population studies indicate that the prevalence may be levelling or even decreasing in some areas in Europe. Since the 1970s, a substantial and ongoing decrease in smoking prevalence has been observed in several European countries including Sweden. The aim of the current study was to estimate the prevalence, characteristics and risk factors for COPD in the Swedish general population. A further aim was to estimate the prevalence trend of COPD in Northern Sweden from 1994 to 2009. Methods: Two large random population samples were invited to spirometry with bronchodilator testing and struc‑ tured interviews in 2009–2012, one in south-western and one in northern Sweden, n = 1839 participants in total. The results from northern Sweden were compared to a study performed 15 years earlier in the same area and age-span. The diagnosis of COPD required both chronic airway obstruction (CAO) and the presence of respiratory symptoms, in line with the GOLD documents since 2017. CAO was defined as post-bronchodilator FEV1/FVC
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