Delirium Acute Brain Dysfunction in the Critically Ill
This text provides a comprehensive, state-of-the-art overview of acute brain dysfunction in the critically ill. The book covers the basic pathophysiology of delirium, epidemiology, risk factors, outcomes associated with delirium, prevention and treatment
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Delirium
Christopher G. Hughes • Pratik P. Pandharipande E. Wesley Ely Editors
Delirium Acute Brain Dysfunction in the Critically Ill
Editors Christopher G. Hughes Critical Illness, Brain Dysfunction, and Survivorship Center and the Division of Anesthesiology Critical Care Medicine Vanderbilt University Medical Center Nashville, TN USA
Pratik P. Pandharipande Critical Illness, Brain Dysfunction, and Survivorship Center and the Division of Anesthesiology Critical Care Medicine Vanderbilt University Medical Center Nashville, TN USA
E. Wesley Ely Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center Department of Medicine Pulmonary and Critical Care Vanderbilt University School of Medicine and the Tennessee Valley Veteran’s Affairs Geriatric Research Education Clinical Center (GRECC) Nashville, TN USA
ISBN 978-3-030-25750-7 ISBN 978-3-030-25751-4 (eBook) https://doi.org/10.1007/978-3-030-25751-4 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
“A long habit of not thinking a thing wrong, gives it a superficial appearance of being right” was written by Thomas Paine in his pamphlet entitled Common Sense circa 1776. And while the context of this statement involved fighting for a democratic government and not fighting disease, the same philosophies hold true for much of our “practice” of medicine. Acute brain dysfunction during acute illness has, unfortunately, proven this concept time and time again throughout the history of medicine. It has long been associated with severe and critical illness, but for practitioners and even patients, it was typically considered an expected and often insignificant consequence – one t
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