Descent of the Testis

This book provides a state of the art overview of all aspects of testicular descent and cryptorchidism, including the mechanisms of descent and the causes, consequences, diagnosis, and treatment of undescended testis. The advances in understanding that ha

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Descent of the Testis

John M. Hutson • Jørgen M. Thorup Spencer W. Beasley

Descent of the Testis Second Edition

John M. Hutson Royal Children’s Hospital University of Melbourne Parkville, Victoria Australia

Spencer W. Beasley University of Otago Christchurch New Zealand

Jørgen M. Thorup Univ. Hospital of Copenhagen Rigshospitalet København Denmark

The first edition of the Work was published in 1992 by HODDER ARNOLD with the following title: Descent of the Testis. ISBN 978-3-319-25908-6 ISBN 978-3-319-25910-9 DOI 10.1007/978-3-319-25910-9

(eBook)

Library of Congress Control Number: 2015957429 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www. springer.com)

Preface

Descent of the testis, or lack thereof, is a subject of great controversy in embryology, endocrinology, and paediatric surgery. For such a common abnormality as undescended testis, it is surprising that there still remain so many unanswered questions, more than 20 years after our first edition (Table 1). This book aims to present up-to-date evidence from our own and other laboratories of the normal mechanisms of testicular descent (Chaps. 2 and 3), along with a brief description of the evolution of descent and the early history of research into its cause (Chap. 1). Chapters 4–10 describe the clinical problems of undescended testes and give our own, necessarily biased, opinion of the best ways to diagnose and treat the anomaly. We have not emphasised hormonal treatment, which has been vigorously proposed by others in recent years, for two major reasons. First, current evidence now suggests that direct or indirect stimulation of androgen secretion only causes relaxation of the cremaster muscle in “retractile” testes, but has little effect on truly undescended testes. Second, lut