Design of Efficient and Safe Neural Stimulators A Multidisciplinary

This book discusses the design of neural stimulator systems which are used for the treatment of a wide variety of brain disorders such as Parkinson’s, depression and tinnitus.  Whereas many existing books treating neural stimulation focus on one part

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Marijn van Dongen Wouter Serdijn

Design of Efficient and Safe Neural Stimulators A Multidisciplinary Approach

Analog Circuits and Signal Processing Series Editors: Mohammed Ismail, Dublin, USA Mohamad Sawan, Montreal, Canada

More information about this series at http://www.springer.com/series/7381

Marijn van Dongen • Wouter Serdijn

Design of Efficient and Safe Neural Stimulators A Multidisciplinary Approach

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Marijn van Dongen NXP Semiconductors N.V. Nijmegen, The Netherlands

Wouter Serdijn Delft University of Technology Delft, The Netherlands

ISSN 1872-082X ISSN 2197-1854 (electronic) Analog Circuits and Signal Processing ISBN 978-3-319-28129-2 ISBN 978-3-319-28131-5 (eBook) DOI 10.1007/978-3-319-28131-5 Library of Congress Control Number: 2016930305 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www. springer.com)

En dit is de reeden, dewelke my beweegt, om eenige experimenten, die ik al over lang omtrent deeze zaak gedaan heb, in het ligt te geeven, en alzoo ik die van een zeer groote consequentie en gewigt oordeel, zoo zou ookmyn verzoek zyn, omdie ernstig te willen naadenken, en op den toetsteen der waarheid te stellen Jan Swammerdam, Bybel der natuure, 1737

Preface

Electrical neural stimulation is an established treatment methodology for an increasing number of neural pathologies, while its application is under consideration for an even larger number of diseases. In line with this development, there is a need for neural stimulator devices that are safe and reliable and have a small form factor. The design of such devices requires a multidisciplinary approach, combining the needs from neurological, physiological, electrochemical, and electrical perspectives. The concept of electrical stimulation is typically approached from two dis