Development of the Knee Quality of Life (KQoL-26) 26-item questionnaire: data quality, reliability, validity and respons
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Development of the Knee Quality of Life (KQoL-26) 26-item questionnaire: data quality, reliability, validity and responsiveness Andrew M Garratt1,2, Stephen Brealey*2, Michael Robling3, Chris Atwell3, Ian Russell4, William Gillespie5, David King6 for the DAMASK Trial Team Address: 1National Resource Centre for Rehabilitation in Rheumatology, Pb 23, Vinderen, 0319 Oslo, Norway, 2Department of Health Sciences, York Trials Unit, Seebohm Rowntree Building, University of York, Heslington, York YO10 5DD, UK, 3Department of Primary Care and Public Health, Cardiff University, Neuadd Meirionydd, Heath Park, Cardiff, CF14 4YS, UK, 4Institute of Medical and Social Care Research, Brigantia Building, Penrallt Road, University of Wales Bangor, Gwynedd, LL57 2AS, UK, 5Hull York Medical School, University of York, York, YO10 5DD, UK and 6X-ray Department, York Hospital, Wigginton Road, York, YO31 8HE, UK Email: Andrew M Garratt - [email protected]; Stephen Brealey* - [email protected]; Michael Robling - [email protected]; Chris Atwell - [email protected]; Ian Russell - [email protected]; William Gillespie - [email protected]; David King - [email protected] * Corresponding author
Published: 10 July 2008 Health and Quality of Life Outcomes 2008, 6:48
doi:10.1186/1477-7525-6-48
Received: 18 June 2007 Accepted: 10 July 2008
This article is available from: http://www.hqlo.com/content/6/1/48 © 2008 Garratt et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract Background: This article describes the development and validation of a self-reported questionnaire, the KQoL-26, that is based on the views of patients with a suspected ligamentous or meniscal injury of the knee that assesses the impact of their knee problem on the quality of their lives. Methods: Patient interviews and focus groups were used to derive questionnaire content. The instrument was assessed for data quality, reliability, validity, and responsiveness using data from a randomised trial and patient survey about general practitioners' use of Magnetic Resonance Imaging for patients with a suspected ligamentous or meniscal injury. Results: Interview and focus group data produced a 40-item questionnaire designed for selfcompletion. 559 trial patients and 323 survey patients responded to the questionnaire. Following principal components analysis and Rasch analysis, 26 items were found to contribute to three scales of knee-related quality of life: physical functioning, activity limitations, and emotional functioning. Item-total correlations ranged from 0.60–0.82. Cronbach's alpha and test retest reliability estimates were 0.91–0.94 and 0.80–0.93 respectively. Hypothesised correlations with the Lysholm Knee Scale, EQ-5D, SF-36 and knee symptom questions
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