Diabetes and treatment with orally administrated corticosteroids negatively affect treatment outcome at follow-up after
- PDF / 523,753 Bytes
- 9 Pages / 595.276 x 790.866 pts Page_size
- 9 Downloads / 164 Views
ANKLE
Diabetes and treatment with orally administrated corticosteroids negatively affect treatment outcome at follow‑up after acute Achilles tendon rupture Allan Cramer1 · Nanna Cecilie Jacobsen1 · Maria Swennergren Hansen1,2 · Håkon Sandholdt3 · Per Hölmich1 · Kristoffer Weisskirchner Barfod1 Received: 4 August 2020 / Accepted: 5 November 2020 © European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2020
Abstract Purpose Studies investigating the influence of comorbidities on patient-reported outcomes after acute Achilles tendon ruptures (ATR) are lacking. In this study, the aim was to investigate the effect of comorbidity and medical treatment on the patient-reported outcome measure Achilles tendon total rupture score (ATRS). Methods The study was performed as a registry study from the Danish Achilles tendon Database (DADB). In the DADB, ATRS was registered at baseline (prior to rupture), at 3–6 month, 1-year and 2-year follow-ups. The outcomes were ATRS at follow-up and the change in ATRS from baseline to follow-up. Variables of interest were diabetes, hypertension, rheumatic disease and treatment with orally administrated corticosteroids. Linear mixed-effects models including all follow-up time points in the same model were used adjusting for sex, age group, treatment (operative or non-operative) and the investigated comorbidities. Results Data were collected from 2012 to 2019. Two thousand and four patients with ATR were included. Patients with the investigated comorbidities and treatment with orally administrated corticosteroid scored 10.6–19.1 points lower in mean ATRS at baseline (prior to rupture) compared to patients without the respective disease or treatment. At follow-up, patients with diabetes (mean difference, [95% CI]) (− 6.2, [− 11.7; − 0.8]; P = 0.03) and patients in treatment with orally administrated corticosteroids (− 10.9, [− 16.2; − 5.7]; P
Data Loading...
