Diagnostic performance of 3T stress magnetic resonance myocardial perfusion imaging (MRMPI) using 32-channel cardiac coi
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POSTER PRESENTATION
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Diagnostic performance of 3T stress magnetic resonance myocardial perfusion imaging (MRMPI) using 32-channel cardiac coil in patients with coronary artery disease Chun-Ho Yun1*, Jui-Peng Tsai1, Tien-Yu Wu1, Cheng-Ting Tsai1, Ricardo C Cury2 From 2011 SCMR/Euro CMR Joint Scientific Sessions Nice, France. 3-6 February 2011 Background/aim With newly available 32-channel cardiac coil, 3 tesla MRI system provides increased signal-to-noise radio (SNR), reduced imaging time and improved spatial resolution. This study sought to determine the diagnostic performance of 3T stress MRMPI with 32-channel cardiac coil in detecting clinical relevant coronary artery stenosis in comparison with invasive coronary angiography (ICA). Methods Forty four patients (29 men; mean age: 61year) who were scheduled for ICA underwent stress MRMPI with 3T MRI (Achieva 3T, Philips) with a 32-channel cardiac receiver coil ( Invivo, Gainesville, FL). The total amount of contrast medium (Multihance, Bracco) was 0.15mmole/kg with injection rate at 4ml/s. The MR protocol included gadolinium-enhanced stress first-pass perfusion (0.56mg/kg, dipyridamole), rest perfusion, and delayed enhancement (DE). Ischemia was defined as (1) a territory with perfusion defect at stress study but no DE, (2) territory with DE but additional peri-infarcted perfusion defect at stress study. Diagnostic performance was determined on a per-patient basis. Quantitative CA served as the reference standard. Results Coronary angiography depicted significant stenosis (≥70% stenosis at epicardial coronary artery) in 22 of 44 patients (50%). No complications were observed during 1
Mackay Memorial Hospital, Taipei, Taiwan Full list of author information is available at the end of the article
Figure 1 Image of a patient demonstrating stress-inducible subendocardial perfusion defect (black arrow) at basal anterior and antero-septal walls during stress study (A); but not during rest study (B). No delayed enhancement is present in the anterior wall.(C). Invasive coronary angiography shows high grade edge instent restenosis (white arrow) of LAD-p (D).
Stress perfusion 3.0 tesla MRI and dipyridamole infusion. For detection of significant coronary stenosis, 3T stress MRMPI provided sensitivity: 0.91(0.75-1.00), specificity: 0.86(0.72-1.00), positive predictive value: 0.87 (0.74-1.00) and negative predictive value: 0.91(0.7481.00). The overall diagnostic accuracy was: 0.88.
Conclusion Our study showed that 3T stress MRMPI using 32-channel cardiac coil demonstrated high diagnostic
© 2011 Yun et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Yun et al. Journal of Cardiovascular Magnetic Resonance 2011, 13(Suppl 1):P95 http://jcmr-online.com/content/13/S1/P95
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