Differential diagnosis of hypervascular ultra-small renal cell carcinoma and renal angiomyolipoma with minimal fat in ea

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KIDNEYS, URETERS, BLADDER, RETROPERITONEUM

Differential diagnosis of hypervascular ultra‑small renal cell carcinoma and renal angiomyolipoma with minimal fat in early stage by using thin‑section multidetector computed tomography Xu Wang1,2 · Ge Song1,2 · Jihong Sun3 · Guoliang Shao1,2

© Springer Science+Business Media, LLC, part of Springer Nature 2020

Abstract Purpose  The purpose of this study was to investigate the difference between imaging features of ultra-small renal cell carcinoma (usRCC) and angiomyolipoma with minimal fat (mfAML) whose enhancement were both hypervascular by using multidetector computed tomography (MDCT). Materials and methods  Confirmed by pathology, 40 cases of hypervascular usRCC and 21 cases of hypervascular mfAML both with diameter of 2 cm or less were compared and analyzed retrospectively, including traditional imaging features and thin-section computed tomography (CT) dynamic enhanced parameters. Meanwhile, receiver operating characteristic (ROC) curves were constructed to evaluate the diagnostic efficacy of each significant parameter and the information with diagnostic value was selected to construct the prediction model. Results  Comparison of traditional imaging features: the features, included age, shape, location, central location of tumor, wedge sign, renal cortex lift sign, black star sign, enhanced homogeneity in cortical phase (CP) and enhancement pattern had no significant difference between usRCC and mfAML (P > 0.05); sex, cystic degeneration or necrosis, pseudocapsule sign, and enhanced homogeneity in nephrographic phase (NP) had significant differences between usRCC and mfAML (P