Differential effects of different delivery methods on progression to severe postpartum hemorrhage between Chinese nullip
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RESEARCH ARTICLE
Open Access
Differential effects of different delivery methods on progression to severe postpartum hemorrhage between Chinese nulliparous and multiparous women: a retrospective cohort study Chang Xu1†, Wanting Zhong2†, Qiang Fu3, Li Yi1, Yuqing Deng1, Zhaohui Cheng4, Xiaojun Lin5, Miao Cai3, Shilin Zhong1, Manli Wang6*, Hongbing Tao7, Haoling Xiong7, Xin Jiang1 and Yun Chen1
Abstract Background: Delivery methods are associated with postpartum hemorrhage (PPH) both in nulliparous and multiparous women. However, few studies have examined the difference in this association between nulliparous and multiparous women. This study aimed to explore the difference of maternal and neonatal characteristics and delivery methods between Chinese nulliparous and multiparous women, and then examine the differential effects of different delivery methods on PPH between these two-type women. Methods: Totally 151,333 medical records of women who gave birth between April 2013 to May 2016 were obtained from the electronic health records (EHR) in a northern province, China. The severity of PPH was estimated and classified into blood loss at the level of < 900 ml, 900–1500 ml, 1500–2100 ml, and > 2100 ml. Neonatal and maternal characteristics related to PPH were derived from the same database. Multiple ordinal logistic regression was used to estimate associations. (Continued on next page)
* Correspondence: [email protected] † Chang Xu and Wanting Zhong contributed to this work equally and should be regarded as co-first authors. 6 China Center for Special Economic Zone Research, Shenzhen University, Shenzhen 518060, Guangdong, China Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
Xu et al. BMC Pregnancy and Childbirth
(2020) 20:660
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Results: Medical comorbidities, placenta previa and accreta were higher in the nulliparous group and the episiotomy rate was higher in the multiparo
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