Diffuse Lung Disease A Practical Approach

Interstitial lung diseases comprise a significant part of any respiratory medicine practice.  This timely second edition of Diffuse Lung Disease is a practical clinically-oriented resource, covering all the major advances in diagnostic techniques and

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Robert P.  Baughman Roland M. du Bois Editors

Diffuse Lung Disease A Practical Approach Second Edition

Editors Robert P. Baughman, MD Department of Internal Medicine University of Cincinnati College of Medicine Cincinnati, OH, USA [email protected]

Roland M. du Bois, MD Emeritus Professor of Respiratory Medicine Imperial College London, UK [email protected]

ISBN 978-1-4419-9770-8     e-ISBN 978-1-4419-9771-5 DOI 10.1007/978-1-4419-9771-5 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011939745 © Springer Science+Business Media, LLC 2012 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal ­responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface

Introduction Interstitial lung diseases, taken together, comprise a significant component of any respiratory medicine clinician’s practice. This has been a rapidly changing field, with the emergence of new diagnostic techniques and therapies. In 2004, we edited the first edition of “Diffuse Lung Disease: a practical approach.” In this second edition, we are not only updating what was presented in the first edition, but also providing information about many exciting new advances that have been made in many of this complex group of diseases over the last 7  years. The overall goal of this book remains the same – to provide the reader with clear and specific recommendations regarding the management of all forms of interstitial lung disease. These recommendations are provided by a group of physicians who are all experts in the areas on which they are contributing. The book is divided into two major sections. The first section deals with general aspects of diagnosis and management of interstitial lung disease, including: the clinician’s approach to patient evaluation (Myers and Raghu); the radiologist’s approach to thoracic imaging with a major focus on the role of the high-resolution CT scan (Lynch); the added value of bronchoalveolar lavage (Drent and Linssen); a