Disease-Specific Health-Related Quality of Life Instruments

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Disease Reservoir in Human African Trypanosomiasis (HAT) Definition Pool of infected humans or animals that are a source of infection and therefore drive the transmission of Human African Trypanosomiasis (HAT). Screening and treatment programs aiming at eliminating the HAT reservoir has always been the cornerstone of the control of West African sleeping sickness. Actions targeting the animal reservoir are common in East African sleeping sickness but the role of an animal reservoir in West African sleeping sickness is unclear.

Disease-Specific HRQOL Measures Definition Disease-Specific Measures are developed for a specific disease and may give a more appropriate, comprehensive and a more unique picture of the disease. Important and perhaps more meaningful data may thus be captured and this may help to pinpoint aspects of a disease that may need intervention. Thus, these measures may be more sensitive to subtle changes in HRQOL compared to generic measures.

Disease-Specific Instruments Disease State Definition A pathological condition of a part, organ, or system of an organism, resulting from various causes, such as infection, genetic defect, or environmental stress, and characterized by an identifiable group of signs or symptoms.

Definition Health-related quality of life assessment instruments which have been developed specifically to assess the concept within a unique pathology.

Disease-Specific Questionnaires Disease-Controlled Days Definition An effectiveness criterion or metric, this refers to the number of days within a year that the disease was considered controlled.

Disease-Specific HealthRelated Quality of Life Instruments Definition Instrument devised to assess the impact of the function of the affected organ, and the organ-related symptoms and morbidity on the patient health-related quality of life.

Definition Diseaseā€Specific Questionnaires cover many items that are more relevant to patients with a certain type of disease. Their specific nature enable them to be sensitive to minor relevant changes and they are used to detect small differences between groups and for evaluation of treatments or interventions.

Disease-Specific Tools Definition Disease-Specific Tools are developed for specific diagnostic groups of individuals, measuring areas relevant to the particular disease and treatment.

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