Donor-Tissue Splitting and Tissue Storage for DALK and DMEK Surgery
For more than a century, penetrating keratoplasty has been the gold standard for corneal transplantation, but tremendous progress has been made in recent years in improving lamellar keratoplasty techniques, such as deep anterior lamellar keratoplasty (DAL
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Claus Cursiefen Albert S. Jun Editors
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Current Treatment Options for Fuchs Endothelial Dystrophy
Claus Cursiefen • Albert S. Jun Editors
Current Treatment Options for Fuchs Endothelial Dystrophy
Editors Claus Cursiefen Department of Ophthalmology University of Cologne Cologne Germany
Albert S. Jun Wilmer Eye Institute Johns Hopkins Medical Institutions Baltimore Maryland USA
ISBN 978-3-319-43019-5 ISBN 978-3-319-43021-8 DOI 10.1007/978-3-319-43021-8
(eBook)
Library of Congress Control Number: 2016956895 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland The registered company address is Gewerbestrasse 11, 6330 Cham, Switzerland
Foreword
When Ernst Fuchs described what we now call Fuchs endothelial dystrophy (FED) in 1910, he was so humble to state that the disease origin may in fact later be discovered as not epithelial in nature – as he thought in times without slit-lamp examination. We nowadays in fact know that FED is primarily an endothelial disease, and we obviously now know much more, as this book tries to define in state-of-the-art fashion. But we certainly should remain as humble as Fuchs in that we still do not understand large aspects of FED pathogenesis and treatment. Fortunately for our patients, in parallel to the growing knowledge of disease mechanisms of FED, the field of lamellar corneal transplant surgery has undergone a revolution in recent years so that we can offer much better and safer treatment options such as DSAEK and DMEK. This book aims to provide a thought-provoking overview of all aspects of FED, from pathogenesis to modern surgical and cellular therapy. We hope that this work even further stimulates progress toward our goals to gain better insights into disease mechanisms and to develop even safer and better treatment options
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