Early thromboelastography in acute traumatic coagulopathy: an observational study focusing on pre-hospital trauma care
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ORIGINAL ARTICLE
Early thromboelastography in acute traumatic coagulopathy: an observational study focusing on pre‑hospital trauma care Alessandra Spasiano1 · Cristina Barbarino1 · Anna Marangone1 · Daniele Orso1 · Giulio Trillò2 · Roberta Giacomello3 · Tiziana Bove1 · Giorgio Della Rocca1 Received: 6 May 2020 / Accepted: 4 September 2020 © The Author(s) 2020
Abstract Background Major brain injury and uncontrolled blood loss remain the primary causes of early trauma-related mortality. One-quarter to one-third of trauma patients exhibit trauma-induced coagulopathy (TIC). Thromboelastometry (ROTEM) and thrombelastography (TEG) are valuable alternatives to standard coagulation testing, providing a more comprehensive overview of the coagulation process. Purpose Evaluating thromboelastographic profile, the incidence of fibrinolysis (defined as Ly30 > 3%) in severe trauma patients, and factors influencing pathological coagulation pattern. Methods Prospective observational 2 years cohort study on severe trauma patients assisted by Helicopter Emergency Medical System (HEMS) and Level 1 Trauma Center, in a tertiary referral University Hospital. Results Eighty three patients were enrolled, mean NISS (new injury severity score) 36 (± 13). Mean R value decreased from 7.25 (± 2.6) to 6.19 (± 2.5) min (p 40 groups, changes in R value increased their significance (p = 0.04 and p 27, MA
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