Edaravone

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Edaravone Anaphylactic reaction: case report In a independent, blinded survey of real-world data on adverse events from postmarketing pharmacovigilance reports from 8 August 2017 to 3 August 2018, a man [age not stated] was described, who developed anaphylactic reaction manifesting as trouble breathing/swallowing after sixth infusion of edaravone [Radicava; dosage not stated] for amyotrophic lateral sclerosis. He was treated with unspecified steroid, after which the anaphylactic reaction resolved. Author comment: "Review for serious anaphylactic reaction/hypersensitivity revealed one report (a man who experienced trouble breathing/swallowing after his 6th infusion, which resolved with steroid treatment)." Jackson C, et al. Radicava (edaravone) for amyotrophic lateral sclerosis: US experience at 1 year after launch. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration 20: 605-610, No. 7-8, 2019. Available from: URL: http:// 803435948 doi.org/10.1080/21678421.2019.1645858 - USA

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Reactions 23 Nov 2019 No. 1780