Effect of over/under-expanding on the mechanical behavior in provisional stenting using bioresorbable scaffold
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DOI 10.1007/s12206-020-0514-8
Journal of Mechanical Science and Technology 34 (6) 2020 Original Article DOI 10.1007/s12206-020-0514-8 Keywords: · Bioresorbable polymer · Bioresorbable scaffold strain analysis · Bifurcation lesion · Provisional stenting · Finite element analysis
Correspondence to: Pruthvi Serrao [email protected]
Citation: Kim, J. Y., Park, S., Serrao, P. (2020). Effect of over/under-expanding on the mechanical behavior in provisional stenting using bioresorbable scaffold. Journal of Mechanical Science and Technology 34 (6) (2020) 2371~2376. http://doi.org/10.1007/s12206-020-0514-8
Received January 21st, 2020 Revised
March 16th, 2020
Accepted April 1st, 2020 † Recommended by Editor Chongdu Cho
Effect of over/under-expanding on the mechanical behavior in provisional stenting using bioresorbable scaffold Jang Yong Kim1, Sungsu Park2 and Pruthvi Serrao3 1
Division of Vascular and Transplant Surgery, College of Medicine, The Catholic University of Korea, 2 Seoul, Banpo-daero 222, Korea, Korea Gas Technology Corporation, 1227, Daedeok-daero, Yuseong3 gu, Daejeon 34007, Korea, R&D Department, Coetec Co. Ltd, 40-9, Baekjegobun-ro 27-gil, Songpa-gu, Seoul, Korea
Abstract
The purpose of this study is to contribute to the design and development by analyzing the expected mechanical behavior of bioresorbable scaffolds. Bioresorbable scaffolds are a type of medical device ‘stent’ that treats heart disease by physically removing plaque inside the coronary arteries. Unlike conventional metal-based stents, bioresorbable scaffolds are manufactured using polymeric materials that achieve dissolution properties within 1-2 years in vivo through hydrolysis with blood. Thus, bioresorbable scaffolds have the advantage of reducing postoperative side effects. However, due to the mechanical properties of the polymeric materials used, bioresorbable scaffolds are currently only applied to simple lesions. In particular, for branched lesions that separate from one main vessel into two branched vessels, the stenting procedures are still being studied through various clinical trials, but there are not many reports of studies and results through interpretation. A provisional stent method of placing a single stent in the blood vessel is commonly used to treat branched lesions. Since the diameter of the blood vessel before and after the branching is different, the selection of the stent diameter is applied as the first step before the stent operation. Conventional metal-based stent operations do not require this consideration, but it is needed for bioresorbable scaffolds due to the low tensile strength of the polymeric material. In this study, temporary stents with two different diameter bioresorbable scaffolds corresponding to the diameter of the main vessel at both ends were evaluated using the calculation method. In this study, these two stents with different diameters were compared in terms of device failure and damage to the inner wall of the blood vessel.
1. Introduction
© The Korean Society of Mechanical Engineers
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