Effect of stellate ganglion block on postoperative recovery of gastrointestinal function in patients undergoing surgery
- PDF / 3,091,351 Bytes
- 11 Pages / 595.276 x 790.866 pts Page_size
- 59 Downloads / 200 Views
RESEARCH ARTICLE
Open Access
Effect of stellate ganglion block on postoperative recovery of gastrointestinal function in patients undergoing surgery with general anaesthesia: a meta‑analysis Bei Wen1, Yajie Wang2, Cong Zhang1 and Zhijian Fu1*
Abstract Background: The return of gastrointestinal function is an important sign of postoperative recovery in patients undergoing surgery with general anaesthesia. We aimed to summarize the effects of stellate ganglion block on the recovery of gastrointestinal function as a means of exploring methods through which anaesthesiologists can contribute to postoperative patient recovery. Methods: We performed a quantitative systematic review of randomized controlled trials published between January 1, 1988, and November 11, 2019, in PubMed, the Cochrane Library, China National Knowledge Infrastructure, Chinese VIP Information, and the Wanfang and SinoMed databases. Study quality was assessed by using the GRADE criteria and bias of included studies were assessed using the revised Cochrane risk-of-bias tool for randomized trials. The time to peristaltic sound resumption, flatus, postoperative eating and the incidence of abdominal bloating in the stellate ganglion block and control groups were compared. The control group consisted of either a stellate ganglion block with normal saline or no treatment. Meta-analysis was performed using Review Manager software. Results: After searching for relevant articles, 281 studies were identified, and five articles with data on 274 patients were eligible. Regarding postoperative flatus time, stellate ganglion block resulted in a mean reduction of 15 h (P = 0.02); then a sensitivity analysis was performed, and the standard mean difference decreased to 6 h (P = 0.007). For gastrointestinal surgery, the mean reduction was 23.92 h (P = 0.0002). As for the evaluation of the recovery of peristaltic sounds, stellate ganglion block promoted the recovery of regular peristaltic bowel sounds an average of 14.67 h earlier than in the control (P = 0.0008). When it comes to nutrients, stellate ganglion block shortened the total parenteral nutrition time by more than 50 h in patients who had undergone gastrointestinal surgery (P 18 years of age. Combined text and MeSH terms were used for searching; the detailed search strategies are described in Additional file 1: Appendix A. All potentially eligible studies were considered for review irrespective of the primary outcome. Manual searches were performed using the reference lists of crucial articles.
Wen et al. BMC Surg
(2020) 20:284
Page 3 of 11
Inclusion and exclusion criteria
Moreover, if the heterogeneity was high, a sensitivity analysis was performed to explore the cause of it. Publication bias was assessed using a funnel plot. We used the Cochran I2 test to assess the existence and magnitude of heterogeneity among the studies [11]. Heterogeneity was considered low, moderate, or high for I2 values 50%, respectively. Review Manager (RevMan 5.3) and Stata 14.0 was used in all statistical analyses.
Data Loading...
