Eltrombopag

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Transient liver toxicity: case report In a retrospective study of six patients, one patient [age and sex not stated] was described, who developed transient liver toxicity during treatment with eltrombopag for severe aplastic anaemia (SAA). The patient was diagnosed with SAA, which was refractory to an unspecified immunosuppressive therapy in the past. Thereafter, the patient started receiving eltrombopag [dosage and route not stated] and developed eltrombopag-related grade 1 transient liver toxicity [duration of treatment to reaction onset not stated]. Author comment: "A grade 1 Eltrombopag-related transient liver toxicity was observed in 1 pt." Finelli C, et al. Eltrombopag treatment for aplastica anemia refractory to immunosuppressive treatment: Retrospective study of 6 patients from a single institution. Haematologica 104 (Suppl. 2): 58-59 (plus poster) abstr. P008, Oct 2019. Available from: URL: https://www.ncbi.nlm.nih.gov/pmc/journals/820/ 803434014 [abstract] - Italy

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Reactions 16 Nov 2019 No. 1779