Encapsulation of active fractions of whey proteins with antioxidant potential in pectin-collagen and pectin-gelatin micr
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MRS Advances © 2019 Materials Research Society DOI: 10.1557/adv.2019.33
Encapsulation of active fractions of whey proteins with antioxidant potential in pectin-collagen and pectin-gelatin microparticles Jazmin Castillo Sanabria1, Claudia Rosario Muro Urista1*, Rosa Elena Ortega Aguilar1, Javier Illescas1, María del Carmen Díaz Nava1, Guillermo Carbajal Franco1 1 Tecnológico Nacional de México/Instituto Tecnológico de Toluca, División de Estudios de Postgrado e Investigación, México.
ABSTRACT
The aim of the present research was to evaluate pectin-gelatine and pectin-collagen polymeric compounds as encapsulating and releasing matrices for whey active peptides with antioxidant properties. Active peptides were obtained by hydrolysis of whey proteins with thermolysin and proteinase enzymes from B. subtilis. The hydrolysates were fractioned and encapsulated in the pectin composite matrices to obtain particles loaded with active whey peptides. The composite particles were analysed by SEM and IR techniques. In addition, they were also tested under simulated gastric conditions to evaluate the encapsulation efficiency and delivering power of the composite materials. The results showed that both encapsulation particles were excellent supports, because they retained to-the peptides and maintained their antioxidant activity during the simulated gastric process (120 min). However, the pectin gelatine particles were digested faster than those of pectin-collagen. The peptides fromencapsulated in pectin-gelatine were released within this time, showing an increment in theantioxidant activity. Peptides from gelatine protein were also released by the gastric enzymes, and thus also they contributed to the antioxidant activity; in addition to the whey peptides.
1. INTRODUCTION Since decades, many researchers have focused on the study of whey proteins and its-their derived peptides, because they are considered bioactive molecules with specific health benefits. Due to their functional and therapeutic properties, there are several reports in the literature on the activity of peptides in animal model systems, such as antihypertensive activity, immunomodulatory, antithrombotic and antibacterial
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activity, which are of great interest to the pharmaceutical, food and cosmetic areasindustries [11]. In this perspective, bioactive peptides have mainly been incorporated as ingredients in functional foods, nutraceuticals, and they are currently also studied as pharmaceutical molecules to assist in the control and prevention of diseases [2]. However, serum molecules are considered complex substances, as they are susceptible to degradation and instability. In particular, it has been demonstrated, that when they are oral delivering, their instability is increased and they are degraded by the gastric enzymes; thus
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