Endobronchial ultrasound-guided Transbronchial needle aspiration (EBUS-TBNA) in simulator lesions of pulmonary pathology
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(2020) 20:246
CASE REPORT
Open Access
Endobronchial ultrasound-guided Transbronchial needle aspiration (EBUSTBNA) in simulator lesions of pulmonary pathology: a case report of pulmonary Myospherulosis Liliana Fernández-Trujillo1,2* , Santiago Sanchez3,4, Saveria Sangiovanni-Gonzalez5, Eliana I. Morales5,6, Mauricio Velásquez2,7 and Luz F. Sua2,8
Abstract Background: Myospherulosis develops as the result of a reaction between exogenous lipids and red blood cells (RBC) of the patient, being the latter injured when perceived as a foreign body by the immune system, triggering an intense inflammatory response. Case presentation: A 63-year-old man with a history of dyslipidemia, Barret’s esophagus, and coronary disease, who was taken to thoracoscopy and left inferior lobectomy due to the presence of a pulmonary mass. A primary pulmonary adenocarcinoma was diagnosed. On follow up a PET-CT was performed, in which a metabolically active lesion was described adjacent to the prior lobectomy, suggesting a local relapse. EBUS-TBNA was then performed, obtaining a sample from which histopathological pattern compatible with myospherulosis was obtained. Conclusions: Although it is a rare entity, myospherulosis has a well-defined morphological pattern. By not recognizing myospherulosis as a benign lesion, a patient’s risk of invasive cancer can be overestimated. It is a phenomenon found with increasing frequency and has been reported in different tissues, however, this is the first report in the literature of myospherulosis of the lung. Greater awareness is required regarding the existence of this phenomenon. Keywords: Myospherulosis, EBUS-TBNA, Pulmonary disease, Lung Cancer, Case report
* Correspondence: [email protected]; [email protected]; [email protected] 1 Department of Internal Medicine, Pulmonology Service, Interventional Pulmonology, Fundación Valle del Lili, Avenida Simón Bolívar. Cra. 98 No.18-49, Tower 6, 4th Floor, Cali, Colombia 760032 2 Faculty of Health Sciences, Universidad Icesi, Calle 18 # 122-135, Cali 760032, Colombia Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commo
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