Epigenetic Epidemiology

The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance.  Epigenetics plays an  important role in shaping who we are and contributes to our prospects of health and disease.  While early epigenetic re

  • PDF / 80,109 Bytes
  • 6 Pages / 439.37 x 666.14 pts Page_size
  • 30 Downloads / 204 Views

DOWNLOAD

REPORT


A Adaptive plasticity, 108 Addiction, 356 Age, 2, 16, 26, 70, 94, 111, 128, 140, 165, 185–193, 203, 232, 274, 293, 311, 324, 344, 390, 402, 429 Aging, 11, 13–18, 94, 166, 187–190, 192, 193, 198, 203–204, 209, 210, 212, 213, 230, 232, 233, 251, 313, 344, 346–348, 431 Agouti gene, 95, 110, 392 Agouti mouse, 110, 392 Air pollution, 198, 209–210, 310, 313–315, 334 Alcohol, 23, 29, 32, 200–203, 211, 231, 232, 236, 274, 294 Allergic disease, 314–315 Alzheimer’s disease (AD), 24, 174, 202, 350, 360 Analysis of variance, 63, 66, 69, 166, 176 Angelman Syndrome (AS), 118, 119, 130–133, 139, 140, 142, 147–150, 211, 323, 324, 348, 359, 416 Arcsine transformation, 61, 63 Arsenic, 198, 208, 239, 313 Asbestos, 210 Assisted reproductive technology (ART), 2, 117–133, 171, 211 Association, 1, 2, 22, 26, 27, 30, 31, 42, 62–64, 66–73, 80, 93, 106, 110, 118, 122, 125, 126, 129, 130, 132, 133, 157, 168–170, 172, 175, 186, 190, 200–205, 208, 210, 211, 231–234, 236–243, 245, 246, 248–250, 274, 294, 296, 310–315, 331, 346, 350, 352–359, 379, 388, 389, 391, 402–404, 408, 415, 433

Asthma, 2, 24, 307–316 Atherosclerosis, 2, 192, 423–434 Autism, 2, 321–335 Autism spectrum disorder, 324, 325, 331, 348, 351 Autoimmune diabetes, 380–385, 390 Autoimmune disease, 292, 293, 295, 297, 378, 379, 390

B Beckwith-Wiedemann syndrome (BWS), 108, 118, 125–130, 133, 143–147, 173, 211, 416 Benzene, 17, 207, 232, 245 Beta distribution, 61, 73 Beta-cells, 378, 381, 382, 384, 385, 407, 416, 417 Bioinformatics, 25, 31, 40, 49 Biospecimens, 22, 27, 29, 38–39, 168, 179, 296 Bipolar disorder, 176, 349, 359–360 Birth cohort, 26, 28, 29, 353 Birth complication, 352–354 Birthweight, 106, 111 Bisulfite converted DNA, 359, 404 Blood glucose, 383, 386 Body mass index (BMI), 175, 199–202, 391, 412–415 Bonferroni-adjustment, 63, 69, 71, 72 Brain, 12, 18, 22, 24, 89, 106, 107, 131, 149, 153, 188, 209, 247–248, 322–324, 326, 330–333, 346–348, 350, 354–356, 358–362, 364, 409–411

K.B. Michels (ed.), Epigenetic Epidemiology, DOI 10.1007/978-94-007-2495-2, © Springer Science+Business Media B.V. 2012

441

442 C Cancer, 1, 8, 22, 92, 106, 151, 179, 188, 198, 225–251, 271, 308, 358, 415, 425 Candidate gene studies, 59, 62, 63, 66 Cannabis, 355, 356 Carcinogenesis, 14, 18, 193, 204, 213, 227, 231, 232, 237, 240, 241, 243, 270, 275, 282 Cardiovascular disease, 1, 106, 201, 358, 389, 393, 425–427, 433, 434 Case-control study, 22, 26–28, 128, 176, 234, 236, 238, 240–242, 244, 312 CHARM.See Comprehensive high-throughput arrays for relative methylation (CHARM) Childhood abuse, 354–355 Chromatin, 6, 23, 39, 59, 80, 108, 144, 189, 208, 229, 282, 290, 309, 322, 348, 381, 404, 425 Classification, 66, 67, 73, 143, 361, 408, 414 Classification and regression tree (CART), 67, 73 Classification system, 414 Cluster analysis (clustering), 62–68, 72, 73, 249, 356 Cohort, 26–29, 54, 55, 80, 111, 126–130, 132, 178, 201, 231, 234–237, 239, 242, 246, 250, 294, 310–314, 316, 347, 353, 389, 390, 393, 404, 411–415 Cohort study, 26, 27, 29, 128–130, 132, 201, 234, 236, 237, 250, 294, 311, 312, 314, 353