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Ethinylestradiol/norethisterone Decreased libido and hypogonadism in an elderly patient: case report A 68-year-old man with Rendu-Osler disease was referred in December 2003 for management of severe anaemia. Due to disease progression and his increasing need for blood transfusions, ethinylestradiol/ norethisterone 50µg/10mg daily [route not stated] was started in July 2006. His need for blood transfusions began to decrease after 1 month of treatment, but he subsequently reported reduced libido. Laboratory tests revealed hypogonadism, and sildenafil was prescribed [outcome not stated]. Ethinylestradiol/norethisterone was continued until July 2008, when he requested to be switched to octreotide. His condition progressed, and he later died of sepsis due to translocation. Jeanneret S, et al. Rendu-Osler disease: Treatment with oestrogen/progestagen versus octreotide. BMJ Case Reports : 23 Feb 2011. Available from: URL: http:// 803058064 dx.doi.org/10.1136/bcr.11.2010.3534 - Switzerland

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Reactions 30 Jul 2011 No. 1362