Evidence-based Anticancer Materia Medica
Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments’ side effects. In the past, clinical data showed that some comple
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William C. S. Cho Editor
Evidence-based Anticancer Materia Medica
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Editor Dr. William C. S. Cho Department of Clinical Oncology Queen Elizabeth Hospital 13/F, Block R 30 Gascoigne Road Kowloon Hong Kong SAR [email protected]
ISBN 978-94-007-0525-8 e-ISBN 978-94-007-0526-5 DOI 10.1007/978-94-007-0526-5 Springer Dordrecht Heidelberg London New York Library of Congress Control Number: 2011924782 © Springer Science+Business Media B.V. 2011 No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Cover design: deblik, Berlin Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
Preface
Interest in anticancer materia medica is growing in the world, but some clinicians and scientists have queried about the scientific validity of anticancer materia medica due to the lack of scientific evidence. As presenting in my previous book entitled Supportive Cancer Care with Chinese Medicine, a number of laboratory evidences and clinical trials have demonstrated the effectiveness and efficacies of Chinese medicine for supportive cancer care. Accumulating experiments show that some materia medica may have anticancer action by inducing apoptosis and differentiation, enhancing the immune system, inhibiting angiogenesis and proliferation, as well as reversing multidrug resistance. Clinical trials in cancer patients also demonstrate that some materia medica can prolong survival, increase tumor response, improve quality of life, and reduce chemotherapy or radiotherapy toxicity. These findings reveal the potential of materia medica as a promising anticancer therapeutics. Thorough understanding of materia medica and its safety is apparently a prerequisite for all professionals involved and interested in this field. These stimulating interests drove me to compile this unique volume.
William C. S. Cho February 2011
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Contents
1 A n Overview of Anticancer Herbal Medicines ........................................ 1 Addanki P. Kumar, Heather Graham, Craig Robson, . Karthik Garapati and Rita Ghosh 2 A n Evidence-based Perspective of Arsenic Trioxide (As2O3) for Cancer Patients .................................................................................... 37 Hongchi Jiang, Lianxin Liu, Tongsen Zheng and Dalong Yin 3 A n Evidence-based Review of Astragalus Membranaceus (Astragalus) for Cancer Patients............................................................... 65 K. Simon Yeung, Jyothirmai Gubili and Barrie R. Cassileth 4 A n Evidence-based Perspective of Panax Ginseng (Asian Ginseng) and Panax Quinquefolius (American Ginseng) as a Preventing or Supplement
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