Evolution of Atopic Dermatitis in the 21st Century

This comprehensive guide offers a state-of-the-art overview of basic and clinical aspects of atopic dermatitis (AD).The name "atopic dermatitis" was first used in 1933, and Drs. Lewis Webb Hill and Marion B. Sulzberger presented their report "Evolution of

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Ichiro Katayama Hiroyuki Murota Takahiro Satoh Editors

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Evolution of Atopic Dermatitis in the 21st Century

Ichiro Katayama  •  Hiroyuki Murota  Takahiro Satoh Editors

Evolution of Atopic Dermatitis in the 21st Century

Editors Ichiro Katayama Department of Dermatology Integrated Medicine Graduate School of Medicine Osaka University Suita, Osaka, Japan

Hiroyuki Murota Department of Dermatology Integrated Medicine Graduate School of Medicine Osaka University Suita, Osaka, Japan

Takahiro Satoh Department of Dermatology National Defense Medical College Tokorosazawa, Saitama, Japan

ISBN 978-981-10-5540-9    ISBN 978-981-10-5541-6 (eBook) https://doi.org/10.1007/978-981-10-5541-6 Library of Congress Control Number: 2017959195 © Springer Nature Singapore Pte Ltd. 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore

Contents

Part I  Introduction 1 History and Definition ���������������������������������������������������������������������������������� 3 Kiyoshi Nishioka Part II  Epidemiology 2 Epidemiology of Atopic Dermatitis in Japan�������������������������������������������� 13 Takumi Takizawa, Akihiro Morikawa, and Hirokazu Arakawa 3 Epidemiology of Childhood AD in Asian Countries �������������������������������� 25 Yasuyuki Sumikawa 4 Retrospective Cohort Study of Adolescent Atopic Dermatitis���������������� 37 Akiko Kijima, Hiroyuki Murota, and Ichiro Katayama Part III  Genetics 5 Genome-Wide Association Study for Atopic Dermatitis in the Japanese Population ������������������������������������������������������������������������������������������������   45 Mayumi Tamari and Tomomitsu Hirota Pa