Evolutionary Origin of M2 Macrophage Activation: Invertebrates
Phagocytic macrophage-like cells of invertebrates were the first immune cells ever studied scientifically. These cells are described as Amoeba-like (“amoeboid”) cells in the book by Thomas Huxley on invertebrate anatomy in 1878 [1]. In the 1880s, Ilya Met
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Tamás Röszer
The M2 Macrophage
Progress in Inflammation Research Volume 86
Series Editors Michael J. Parnham Inst of Clinical Pharmacology Goethe University Frankfurt Frankfurt am Main, Germany Achim Schmidtko Inst Pharmacology and Clinical Pharmacy Goethe University Frankfurt Frankfurt am Main, Germany
The last few years have seen a revolution in our understanding of how blood and tissue cells interact and of the intracellular mechanisms controlling their activation. This has not only provided multiple targets for potential anti-inflammatory and immunomodulatory therapy, but has also revealed the underlying inflammatory pathology of many diseases. This series provides up-to-date information on the latest developments in the pathology, mechanisms and therapy of inflammatory disease. Areas covered include: vascular responses, skin inflammation, pain, neuroinflammation, arthritis cartilage and bone, airways inflammation and asthma, allergy, cytokines and inflammatory mediators, cell signalling, and recent advances in drug therapy. Each volume is edited by acknowledged experts providing succinct overviews on specific topics intended to inform and explain. The series is of interest to academic and industrial biomedical researchers, drug development personnel and rheumatologists, allergists, pathologists, dermatologists and other clinicians requiring regular scientific updates. More information about this series at http://www.springer.com/series/4983
Tamás Röszer
The M2 Macrophage
Tamás Röszer Institute of Neurobiology Ulm University Ulm, Baden-Württemberg, Germany
ISSN 0379-0363 ISSN 2296-4517 (electronic) Progress in Inflammation Research ISBN 978-3-030-50479-3 ISBN 978-3-030-50480-9 (eBook) https://doi.org/10.1007/978-3-030-50480-9 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is
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