Experimental Transverse Beam Emittance Measurement Using Solenoid Magnet Strength Variation in AB-BNCT

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Experimental Transverse Beam Emittance Measurement Using Solenoid Magnet Strength Variation in AB-BNCT Bong-Hwan Hong, Ilsung Cho, Sun-Hong Min, Seungwoo Park, Minho Kim, Hyunwoo Jung and Chawon Park∗ Korea Institute of Radiological & Medical Sciences, Seoul 01812, Korea (Received 29 September 2020; revised 6 November 2020; accepted 6 November 2020) Boron neutron capture therapy (BNCT) is a more efficient cancer treatment method compared to direct radiation therapy using charged particles such as protons or carbon beams. Particularly, accelerator-based BNCT (AB-BNCT) is attracting attention due to easy construction in a hospital. The Korea Institute of Radiological & Medical Sciences (KIRAMS) has constructed an injection system for an electrostatic AB-BNCT accelerator and commissioned 30 keV H− and 5 keV D− ion beam facilities. The beam characteristic parameters and Twiss parameters should be confirmed experimentally, and various methods have to be applied for the related measurements. In this study, the linear matrix formalism is used as a technique to measure the beam characteristic and Twiss parameters by varying the magnetic field strength of a solenoid in the beam line. To confirm the validity of this method, a multi-particle tracking code was executed. The simulation results confirm that the proposed method is effective for extracting Twiss parameters. After verification via the multi-particle tracking code, the method was applied to perform experimental measurements. Notably, the method accurately obtains the transverse beam emittance within reasonable uncertainty levels. Thus, our results show that the proposed method is a convenient technique for extracting the Twiss parameters indirectly. The results of the Twiss parameter measurement can potentially be more precise if other aspects, such as the quadrupole magnetic field strength, are incorporated. Keywords: AB-BNCT, Solenoid magnet, Transverse beam emittance, linear matrix formalism DOI: 10.3938/jkps.77.1159

I. INTRODUCTION Boron neutron capture therapy (BNCT) is a cancer treatment method that efficiently destroys the deoxyribonucleic acid (DNA) of the affected cells. As shown at the top of Fig. 1, BNCT destroys only cancer cells via lithium (Li) and alpha (α) particles released owing to a nuclear reaction that occurs upon irradiating a neutron beam on a tumor in which boron is accumulated using a boron compound on a specific cancer cell. Accelerator-based boron neutron capture therapy (AB-BNCT) is a next-generation cancer treatment technology that is different from proton and heavy particle therapy; moreover it is being increasingly employed worldwide. AB-BNCT has recently attracted attention as an alternative to surgery, chemotherapy, and radiation therapy [1]. The concept of AB-BNCT is described in the bottom of Fig. 1. When a beam of protons or deuterons from an accelerator irradiated onto targets such as Li and beryllium (Be), neutrons are emitted. The emitted fast neutron beams are processed into epi-thermal neutrons using a beam shaping assembly and irradiated o