Febrile Neutropenia
Febrile neutropenia is a common complication in cancer patients and has been studied for more than 30 years. This is a field of cancer in which much progress in supportive care has been made, significantly reducing the morbidity and mortality from infecti
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Springer Berlin Heidelberg New York Barcelona Budapest Hong Kong London Milan Paris Santa Clara Singapore Tokyo
Jean A. Klastersky (Ed.)
Febrile Neutropenia With 11 Illustrations and 32 Tables
Springer
Editor: Jean A. Klastersky Institut Jules Bordet Rue Heger- Bordet 1 B-lOOO Bruxelles Belgium
ISBN-13:978-3-540-61230-8
Library of Congress Cataloging-in-Publication Data Febrile neutropenia 1 J. A. Klastersky (ed.). - Berlin; Heidelberg; New York; Barcelona; Budapest; Hong-Kong; London; Milan; Paris; Santa Clara; Singapore; Tokyo: Springer, 1997 ISBN-13:978-3-540-61230-8 e-ISBN-13:978-3-642-60443-0 DOl: 10.1007/978-3-642-60443-0 NE: Klastersky, Jean A. [Hrsg.]
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Springer-Verlag Berlin Heidelberg 1997
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Preface
Febrile neutropenia is a common complication in the practice of oncology and has been studied for more than 30 years. This is an area of supportive care in cancer in which much progress has been made, significantly reducing the morbidity and mortality of infections resulting from neutropenia. In 1962 McCabe and Jackson reported a 90% mortality rate from gram-negative bacteremia in neutropenic patients; today the figure is below 10%. Thus, tremendous numbers of cancer patients can benefit from specific antineoplastic therapy, having escaped early death from infection. Even greater numbers benefit from the avoidance of infection and from the alleviation of symptoms as a result of effective prophylaxis or adequate therapeutic strategies. These advances have been the result of continuous clinical research backed up by sophisticated microbiology. This research is often carried out by cooperative groups from many institutions because it was appreciated early that only large series can lead to meaningful comparative observations. Initially it was the recognition of the close relationship
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