Fluorouracil/folinic acid/oxaliplatin

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Hepatic damage and mucocutaneous damage: case report A 44-year-old woman developed hepatic and mucocutaneous damage during treatment with folinic acid, fluorouracil and oxaliplatin for heterotopic pancreas adenocarcinoma in the stomach [route, doses; not all outcome stated]. The woman presented with various gastrointestinal symptoms. Gastrointestinal tumour was noted. She underwent gastrectomy. Based on investigations, she was diagnosed to have heterotopic pancreas adenocarcinoma in the stomach. A cyclical chemotherapy with folinic acid, fluorouracil and oxaliplatin [FOLFOX-6 regimen; routes and doses not stated] was started. However, after three cycles, she developed hepatic and mucocutaneous damage due to FOLFOX-6 regimen. Therefore, the woman’s chemotherapy was changed to gemcitabine monotherapy with improvement in cancer markers [outcomes of ADRs not stated]. Xiong Y, et al. Heterotopic pancreas adenocarcinoma in the stomach: A case report and literature review. World Journal of Clinical Cases 8: 1979-1987, No. 10, 26 May 803498831 2020. Available from: URL: http://doi.org/10.12998/wjcc.v8.i10.1979

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Reactions 29 Aug 2020 No. 1819

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