Foundations of Biomedical Knowledge Representation Methods and A

Medicine and health care are currently faced with a significant rise in their complexity. This is partly due to the progress made during the past three decades in the fundamental biological understanding of the causes of health and disease at the molecula

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State-of-the-Art Survey

Arjen Hommersom Peter J.F. Lucas (Eds.)

Foundations of Biomedical Knowledge Representation Methods and Applications

123

Lecture Notes in Artificial Intelligence Subseries of Lecture Notes in Computer Science

LNAI Series Editors Randy Goebel University of Alberta, Edmonton, Canada Yuzuru Tanaka Hokkaido University, Sapporo, Japan Wolfgang Wahlster DFKI and Saarland University, Saarbrücken, Germany

LNAI Founding Series Editor Joerg Siekmann DFKI and Saarland University, Saarbrücken, Germany

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More information about this series at http://www.springer.com/series/1244

Arjen Hommersom Peter J.F. Lucas (Eds.) •

Foundations of Biomedical Knowledge Representation Methods and Applications

123

Editors Arjen Hommersom Institute for Computing and Information Sciences Radboud University Nijmegen The Netherlands

Peter J.F. Lucas Institute for Computing and Information Sciences Radboud University Nijmegen The Netherlands

and Faculty of Management, Science and Technology Open University Heerlen, Limburg The Netherlands

ISSN 0302-9743 ISSN 1611-3349 (electronic) Lecture Notes in Artificial Intelligence ISBN 978-3-319-28006-6 ISBN 978-3-319-28007-3 (eBook) DOI 10.1007/978-3-319-28007-3 Library of Congress Control Number: 2015958082 LNCS Sublibrary: SL7 – Artificial Intelligence © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by SpringerNature The registered company is Springer International Publishing AG Switzerland

Preface

Medicine and health care are currently faced with a significant rise in their complexity. This is partly due to the progress made during the past three decades in the fundamental biological understanding of the causes of health and disease at the molecular, (sub)cellular, and organ level. It is also partly caused by the increased specialization of both biomedical research and clinical practice, and greater involvement o