Gastrointestinal Stromal Tumor Research and Practice
This book provides a comprehensive and up-to-date overview of gastrointestinal stromal tumors (GISTs). GISTs represent the most common mesenchymal neoplasms arising within the gastrointestinal tract. The causative gene of this disease was originally disco
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Gastrointestinal Stromal Tumor
Yukinori Kurokawa • Yoshito Komatsu Editors
Gastrointestinal Stromal Tumor Research and Practice
Editors Yukinori Kurokawa Department of Gastroenterological Surgery Osaka University Graduate School of Medicine Osaka Japan
Yoshito Komatsu Department of Cancer Chemotherapy Hokkaido University Hospital Cancer Center Sapporo Hokkaido Japan
ISBN 978-981-13-3205-0 ISBN 978-981-13-3206-7 (eBook) https://doi.org/10.1007/978-981-13-3206-7 Library of Congress Control Number: 2018968535 © Springer Nature Singapore Pte Ltd. 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Singapore Pte Ltd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore
Foreword
It is my great pleasure and honor to write a foreword for Gastrointestinal Stromal Tumor: Research and Practice. The book systematically covers a broad spectrum from basic knowledge of Gastrointestinal Stromal Tumor (GIST) including epidemiology and clinical guidelines to the latest subjects of molecular diagnosis and treatment by minimal invasive surgery or new agents. It is important that the book has been planned and written in English by leading emerging Japanese specialists in GIST of the next generation based on their scientific knowledge and clinical experience, and now, finally, it is being published. GIST is a rare cancer that has several challenges compared with more common cancers. Generally, physicians may have little experience and knowledge about it because of its rarity. Such rare cancer is known to frequently lack diagnostic criteria and guidelines for standard treatment. Patients with a rare cancer also lack disease information and referral centers as well as medical specialists. Consequently, such patients show poorer prognosi
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