Genetic Basis of Oral Health Conditions
This book explains the genetic basis of a wide range of dental disorders, including dental caries, periodontitis, congenital anomalies, malocclusions, orofacial pain, dental implant failure, and cancer. Such conditions are typically multifactorial or comp
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Genetic Basis of Oral Health Conditions
Alexandre Rezende Vieira
Genetic Basis of Oral Health Conditions
Alexandre Rezende Vieira Oral Biology University of Pittsburgh Pittsburgh, PA USA
ISBN 978-3-030-14484-5 ISBN 978-3-030-14485-2 (eBook) https://doi.org/10.1007/978-3-030-14485-2 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
Human genetics is the discipline that deals with inheritance as it occurs in human beings. It has components of classical genetics, cytogenetics, molecular genetics, biochemical genetics, genomics, population genetics, developmental genetics, clinical genetics, and genetic counseling, and to the list we can now add epigenetics. My main purpose in writing this book is to document the content of 12 years of developing a Craniofacial Genetics course for dental students. The course, as is this book, is designed to use the clinical conditions that interest dentists to present genetic concepts. In that sense, this book brings information that is not typically found in other genetic textbooks or dental textbooks. Similarly to how the course addresses inheritance of dental conditions, the book focuses on inheritance, which is a topic not really explored in publications of the conditions highlighted in the following chapters. This text is the result of more than 20 years of interactions with a number of very talented dental and craniofacial scientists, dentists, and physicians from all continents. I thank Lindsay Carol Brown, Jacob I. Khan, Daryna A. Koval, and Catherine A. Roberts who took my Craniofacial Genetics course and then accepted the challenge to carefully revise the text for grammar, style, and flow s
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