Global Longitudinal Strain: Is It Time to Change the Preoperative Cardiac Assessment of Oncology Patients?
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COMMENTARY
Global Longitudinal Strain: Is It Time to Change the Preoperative Cardiac Assessment of Oncology Patients? Islam Mohammad Shehata . Tiffany D. Odell . Amir Elhassan . Ivan Urits . Omar Viswanath . Alan D. Kaye
Received: August 24, 2020 / Accepted: November 10, 2020 Ó The Author(s) 2020
ABSTRACT The introduction of new anticancer treatment modalities has improved survival rates, transforming cancer into a chronic disease in many instances. One of the most devastating complications of cancer treatment is cancer therapyrelated cardiac dysfunction. Adequate preoperative assessment of any significant cancer therapy-related cardiac impairment is critical, and may be missed with conventional measures. The assessment of global longitudinal strain by speckle-tracking echocardiography is more sensitive for the early detection of cardiac contractility before a decline in ejection fraction can be discovered. Global longitudinal strain
I. M. Shehata Department of Anesthesiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt T. D. Odell Department of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA, USA A. Elhassan Cardiothoracic Anesthesia, Desert Regional Medical Center, Palm Springs, CA, USA I. Urits O. Viswanath A. D. Kaye (&) Department of Anesthesiology, Louisiana State University Health Shreveport, Shreveport, LA, USA e-mail: [email protected]
can also predict postoperative cardiac dysfunction, which makes it a good alternative for preoperative cardiac assessment in the oncology population when cancer therapies have been administered that can alter normal performance.
Keywords: Cancer therapy-related cardiac dysfunction; Cardiac dysfunction; Global longitudinal strain; Heart failure; Left ventricular ejection fraction; Oncology; Preoperative cardiac assessment; Speckletracking echocardiography
I. Urits Department of Anesthesia, Critical Care, and Pain Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA O. Viswanath Valley Anesthesiology and Pain Consultants, Envision Physician Services, Phoenix, AZ, USA O. Viswanath Department of Anesthesiology, Creighton University School of Medicine, Omaha, NE, USA O. Viswanath University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA
Oncol Ther
COMMENTARY Key Summary Points Cancer has become a chronic disease due to the introduction of new anticancer strategies. One of the most devastating side effects of cancer treatment is the cancer therapyrelated cardiac dysfunction. which should be considered during the preoperative workup of cancer patients. Traditional 2D echocardiography is limited in its ability to accurately detect left ventricular ejection fraction (LVEF). Speckle-tracking echocardiography is an alternative imaging modality which uses global longitudinal strain and has been shown to improve reliability in the measurement of LVEF. The measurement of left ventricular contractile function by global longitudinal strain might be a more sensitive predictor of cardiac dysfunction, because
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