Glucose metabolism disorder in obese children assessed by continuous glucose monitoring system
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Glucose metabolism disorder in obese children assessed by continuous glucose monitoring system Chao-Chun Zou, Li Liang, Fang Hong, Zheng-Yan Zhao Hangzhou, China
Original article 26
Background: Continuous glucose monitoring system (CGMS) can measure glucose levels at 5-minute intervals over a few days, and may be used to detect hypoglycemia, guide insulin therapy, and control glucose levels. This study was undertaken to assess the glucose metabolism disorder by CGMS in obese children. Methods: Eighty-four obese children were studied. Interstitial uid (ISF) glucose levels were measured by CGMS for 24 hours covering the time for oral glucose tolerance test (OGTT). Impaired glucose tolerance (IGT), impaired fasting glucose (IFG), type 2 diabetic mellitus (T2DM) and hypoglycemia were assessed by CGMS. Results: Five children failed to complete CGMS test. The glucose levels in ISF measured by CGMS were highly correlated with those in capillary samples (r=0.775, P
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