Health Issues in Women with Multiple Sclerosis
This book addresses specific concerns of females affected by multiple sclerosis, where women are disproportionally impacted by the disease. MS is an autoimmune disease of the central nervous system affecting young adults of reproductive age. This book pre
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Maria K. Houtchens A. Dessa Sadovnick Editors
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Health Issues in Women with Multiple Sclerosis
Maria K. Houtchens • A. Dessa Sadovnick Editors
Health Issues in Women with Multiple Sclerosis
Editors Maria K. Houtchens Partners MS Center Brigham and Women’s Hospital Harvard Medical School, Boston Massachusetts USA
A. Dessa Sadovnick MS Clinic UBC Medical Genetics University of British Columbia Faculty of Medicine Vancouver British Columbia Canada
ISBN 978-3-7091-4856-3 ISBN 978-3-7091-4858-7 (eBook) DOI 10.1007/978-3-7091-4858-7 Library of Congress Control Number: 2016961805 © Springer-Verlag Wien 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer-Verlag GmbH Austria The registered company address is: Prinz-Eugen-Strasse 8-10, 1040 Wien, Austria
Foreword
The understanding of pathology and management of multiple sclerosis (MS) has progressed over the last 20 years, as a result of increased basic and clinical research and development of many new effective treatments. MS affects women disproportionately to men and is the most common chronic neurologic illness to affect females of reproductive age. Female MS predominance appears to be increasing over the years. Our understanding of hormonal influences and gender-specific differences on the course of MS, disease progression, and response to therapies has come a long way. Due to improved diagnostic guidelines and the advent and evolution of magnetic resonance imaging (MRI) techniques, the accuracy of the early MS diagnosis has improved. The patients are offered treatments at younger ages. Women with MS must make many life decisions and reproductive choices based on having the specific diagnosis. When planning a pregnancy, important considerations include genetic risk to the offspring, possible effects of pregnancy on the course of MS such as relapses, disability progression and MRI changes, as wel
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