Health-related quality of life in Japanese patients with bladder cancer measured by a newly developed Japanese version o
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ORIGINAL ARTICLE
Health‑related quality of life in Japanese patients with bladder cancer measured by a newly developed Japanese version of the Bladder Cancer Index Takahiro Osawa1 · John T. Wei2 · Takashige Abe1 · Michitaka Honda3 · Shuhei Yamada1 · Jun Furumido1 · Hiroshi Kikuchi1 · Ryuji Matsumoto1 · Kazushi Hirakawa4 · Yasuyuki Sato4 · Yoshihiro Sasaki5 · Toru Harabayashi6 · Norikata Takada6 · Keita Minami7 · Hiroshi Tanaka7 · Ken Morita8 · Akira Kashiwagi9 · Naoto Miyajima9 · Tomoshige Akino9 · Sachiyo Murai1 · Yoichi M. Ito10 · Shunichi Fukuhara11,12 · Katsuhiko Ogasawara13 · Nobuo Shinohara1 Received: 8 June 2020 / Accepted: 11 August 2020 © The Author(s) 2020
Abstract Introduction We validated a Japanese version of the Bladder Cancer Index (BCI) as a tool for measuring health-related quality of life (HRQOL) in bladder cancer patients treated with various surgical procedures. Methods The reliability and validity of the Japanese BCI were examined in 397 Japanese patients with bladder cancer via cross-sectional analysis. The patients simultaneously completed the Short Form (SF)-12, EQ-5D, and the Functional Assessment of Cancer Therapy-General and Bladder (FACT-G and FACT-BL). The differences in BCI subscales among various treatment groups were analyzed. Results This study involved 397 patients (301 males and 96 females), with a mean age of 70 years and a median disease duration of 29 months (IQR: 12–66 months). Of these patients, 221 underwent transurethral resection of a bladder tumor, and 176 patients underwent radical cystectomy (ileal conduit: 101 patients, ileal neobladder: 49, and ureterostomy: 26). Cronbach’s alpha coefficient was ≥ 0.78 for all subscales, except the bowel bother subscale. Despite moderate correlations being detected between the function and bother score in urinary and bowel domains, the sexual function score was inversely correlated with the sexual bother score (r = − 0.19). A missing value percentage of > 15% was associated with old age (p
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