Herbal Medicine in Depression Traditional Medicine to Innovative Dru
This book is written for researchers, undergraduate students and postgraduate students, physicians and traditional medicine practitioners who develop research in the field of neurosciences, phytochemistry and ethnopharmacology or can be useful for their p
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Herbal Medicine in Depression Traditional Medicine to Innovative Drug Delivery
Herbal Medicine in Depression
Clara Grosso Editor
Herbal Medicine in Depression Traditional Medicine to Innovative Drug Delivery
Editor Clara Grosso REQUIMTE/LAQV, Laboratory of Pharmacognosy Department of Chemistry, Faculty of Pharmacy University of Porto Porto, Portugal
ISBN 978-3-319-14020-9 ISBN 978-3-319-14021-6 DOI 10.1007/978-3-319-14021-6
(eBook)
Library of Congress Control Number: 2016937643 © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
Preface
This book was conceived by professionals and researchers from different backgrounds, combining ethnopharmacology, phytochemistry, pharmacology and neuroscience topics, for a better understanding of depression. According to the World Health Organization, more than 350 million people of all ages suffer from depression, and the existing drug therapies are only suitable to treat ca. 60–70 % of patients. Therefore, this book intends to debate the current knowledge on the aetiology of depression, the mechanism of action of the available antidepressants and what routes should be followed to pursue more efficient tools for treatment-resistant patients. This book starts with a general chapter (Chap. 1) dealing with aspects of prevalence and costs of the disease worldwide as well as the theories postulated since the 1950s to explain the physiopathology of depression. The reader will understand that in the light of nowadays knowledge a unified hypothesis of depression is not sustained due to its multifactorial features. Chapter 2 summarizes the mechanism of action of the antidepressant drugs available to treat depression, as well as possible new targets to take into account in new drug discovery programs. Chapters 3 and 4 highlight the impo
