High prevalence of SARS-CoV-2 infection among symptomatic healthcare workers in a large university tertiary hospital in
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RESEARCH ARTICLE
Open Access
High prevalence of SARS-CoV-2 infection among symptomatic healthcare workers in a large university tertiary hospital in São Paulo, Brazil Carolina Palamin Buonafine1, Beatriz Nobre Monteiro Paiatto1, Fabyano Bruno Leal2, Samantha Faria de Matos3, Camila Ohomoto de Morais3, Giovanna Guazzelli Guerra3, Marcus Vinicius Vidal Martuchelli3, Danielle Bruna Leal Oliveira2, Edison Luiz Durigon2, Camila Pereira Soares2, Erika Donizette Candido2, Bruna Larotonda Telezynski2, Marco Aurélio Palazzi Sáfadi1,3* and Flávia Jacqueline Almeida1,3
Abstract Background: Brazil became the epicenter of the COVID-19 pandemic in Latin America since May 2020, reporting the highest number of cases and deaths in the region. Healthcare workers (HCWs) are at increased risk of SARSCoV-2 infection, experiencing a significant burden from COVID-19. Identifying and understanding the clinical characteristics and risk factors associated with infection are of paramount importance to inform screening strategies and infection control practices in this scenario. The aims of this study were to investigate the prevalence and clinical characteristics of HCWs with COVID-19 symptoms. Methods: Between March 21st and May 22nd, 2020 a cross-sectional study was performed in a tertiary university hospital in São Paulo. Prevalence of SARS-CoV-2 infection among HCWs with COVID-19 symptoms was determined by RT-PCR testing on nasopharyngeal and oropharyngeal samples. Participants were asked to complete an electronic structured questionnaire including clinical and demographic data. (Continued on next page)
* Correspondence: [email protected] 1 Department of Pediatrics, Santa Casa de São Paulo School of Medical Sciences, Rua Dr. Cesário Motta Jr., 61, São Paulo, SP 01221-020, Brazil 3 Department of Pediatrics, Division of Infectious Diseases, Santa Casa de São Paulo Hospital, São Paulo, SP, Brazil Full list of author information is available at the end of the article © The Author(s). 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
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