Housekeeping Genes
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H. pylori
hamartoma development in tuberous sclerosis complex.
Hamartoma Definition A hamartoma, or hamartomatous benign tumor characterized by rich mucosa covering branching smooth muscle from the lamina mucosa.
polyp, is a goblet cell bundles of muscularis
Definition ! Helicobacter pylori.
Hairy/E(Spl) Family Definition Hairy/E(spl) family is a group of ! bHLH proteins comprising Hairy, E(Spl), deadpan, Hes-1, Hes-5, Her-1, Her-4, Hesr-1, Sharp-1 and Sharp-2. E(Spl) (Enhancer of split) refers to a gene complex in Drosophila melanogaster that contains a number of target genes of the Notch signaling pathway.
Hamartin Definition Hamartin is the protein encoded by the tumor suppressor gene, TSC1, which is responsible for
Hamartomatous Polyp Definition A hamartomatous polyp, or hamartoma, is a benign tumor characterized by goblet cell rich mucosa covering branching bundles of smooth muscle from the lamina muscularis mucosa.
HAND Gene Family Definition Hand family is a group of bHLH proteins comprising Hand1 and Hand2, which are involved in heart and neural crest development.
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HAND1
HAND1
Haplotype
Definition
Definition
Heart and neural crest derivatives expressed 1 (Hand1), also known as Hxt, Ehand and Thing1, is a ! bHLH protein member of the Hand family. Hand1 is expressed in cytotrophoblastic cells, prenatal and adult heart, and is required for trophoblast giant cell differentiation involved in cardiac looping, ventricular maturation and conotruncal development.
The haplotype is a linked set of alleles associated with one parental genome. It is the particular combination of alleles in a defined region of some chromosome, in effect the genotype in miniature. Originally used to described combinations of ! MHC alleles, it is now used to describe particular combinations of ! RFLPs or ! microsatellite alleles.
HAND2
Haptotaxis
Definition
Definition
Heart and neural crest derivatives expressed 2 (Hand2), also known as Hed, Dhand and Thing2 is a ! bHLH protein member of the Hand family and is involved in heart and neural crest development.
Haptotaxis is the migration of cells in response to an insoluble gradient of chemoattractants.
Haploid Definition Haploid refers to a set of chromosomes containing one copy of each autosome and one sex chromosome; the haploid number n is characteristic of gametes of diploid organisms.
HASH-2 Definition Human achaete-scute complex (Drosophila) homolog-like 2 (Hash-2), also known as Ash2, Hash2 and Ascl2 is a human ! bHLH protein, member of Achaete-scute family. The human ASCL-2 gene locus maps to 11p15.5.
HATH1 Haploinsufficiency Definition Haploinsufficiency describes a situation in which one intact allele of a gene is not able to carry out all functions observable in the presence of both intact alleles.
Definition Human atonal (Drosophila) homolog 1 (Hath1), also known as atonal protein homolog 1 (atoh1) is a ! bHLH protein member of Atonal family of 354 amino acids and 38 kD. The human ATOH1 or ATH1 gene locus maps at 4q22. Hath1 activates ! E-box depende
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