• PDF / 170,213 Bytes
• 1 Pages / 595.245 x 841.846 pts (A4) Page_size
• 69 Downloads / 180 Views

DOWNLOAD

REPORT

---

1 S

Stevens-Johnson syndrome: case report An 11-year-old boy developed Stevens-Johnson (SJS) syndrome following treatment with ibuprofen for fever, and sulfanilamide for lip swelling [dosages not stated; not all routes stated]. The boy was admitted to a hospital in Ukraine, with complaints of fever, bullous lesions on the face, ears, genitals and trunk, erosion and swelling in the lip area, burning sensation in the oral cavity and eyes, general weakness and swallowing difficulty. Anamnesis showed that, he had moderate swelling of the lips 4 days before the onset of these symptoms. Without medical examination, his parents treated the lips with topical sulfanilamide [streptocide] powder, because a few months ago sulfanilamide was prescribed by a doctor when similar symptoms occurred. His parents reported that, prior to this, he had a mild acute respiratory viral infection, manifested by lacrimation, cold and fever. Ibuprofen was given for fever. Subsequently, the catarrhal signs disappeared, but he developed moderate swelling of the lips. Three days later, he had fever, rash all over the body and on the mucous membranes of the eyes and mouth and odynophagia. Clinical examination showed various cutaneous symptoms and investigations showed anaemia, mild leukocytosis, moderate hypoproteinaemia and transient lymphopenia. He was admitted to the ICU. Based on the clinical features, he was diagnosed with SJS. The boy was treated with IV prednisone and dexamethasone, along with unspecified antihistamines, broad-spectrum antibiotics, sodium thiosulfate, topical furacillin and povidone-iodine, quercetin ointment, hydrocortisone ointment, enterosorbents and detoxification therapy with hygienic care of skin and mucous membranes. His condition improved. During the first two days of the treatment, only a few new bullous elements appeared with no new rashes. Eventually, all the bullous elements resolved and epithelisation was noted. After 19 days, he was discharged in a good clinical condition. Chornomydz I, et al. Stevens-johnson syndrome in a child: Case report and minireview. Archives of the Balkan Medical Union 55: 350-357, No. 2, Jun 2020. Available from: 803500345 URL: http://doi.org/10.31688/ABMU.2020.55.2.22

0114-9954/20/1821-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved

Reactions 12 Sep 2020 No. 1821