Impact of angiographic peri-stent contrast staining (PSS) on late adverse events after sirolimus-eluting stent implantat
- PDF / 1,252,733 Bytes
- 11 Pages / 595.276 x 790.866 pts Page_size
- 46 Downloads / 196 Views
ORIGINAL ARTICLE
Impact of angiographic peri-stent contrast staining (PSS) on late adverse events after sirolimus-eluting stent implantation: an observation from the multicenter j-Cypher registry PSS substudy Masao Imai • Takeshi Kimura • Takeshi Morimoto • Naritatsu Saito • Hiroki Shiomi • Ren Kawaguchi • Hakuken Kan • Hiroaki Mukawa • Hiroshi Fujita • Takuo Ishise • Fujio Hayashi • Kazuya Nagao • Shunsuke Take • Hiromasa Taniguchi • Hiroki Sakamoto • Takafumi Yamane • Kinya Shirota • Hiromichi Tamekiyo • Takayuki Okamura • Koichi Kishi • Shinichirou Miyazaki • Satoshi Yamamoto • Kyohei Yamaji • Tomohiro Kawasaki • Eiji Taguchi • Hitoshi Nakajima • Ippei Kosedo • Takeshi Tada • Kazushige Kadota • Kazuaki Mitsudo Received: 25 November 2013 / Accepted: 25 January 2014 Ó Japanese Association of Cardiovascular Intervention and Therapeutics 2014
Abstract This study sought to assess clinical significance of angiographic peri-stent contrast staining (PSS) after sirolimus-eluting stent (SES) implantation in a large multicenter study with 5-year follow-up. The j-Cypher PSS substudy is a multicenter study including 5712 patients (7838 lesions) who underwent follow-up angiographic study within 12 months after SES implantation. Late Electronic supplementary material The online version of this article (doi:10.1007/s12928-014-0248-6) contains supplementary material, which is available to authorized users.
acquired PSS was observed in 184 patients (3.2 %) or 194 lesions (2.5 %). Independent risk factors of PSS were chronic total occlusion and left anterior descending artery lesion, while negative risk factors were in-stent restenosis, diabetes mellitus, C70 years of age, and left circumflex coronary artery lesion. Cumulative incidence of definite very late stent thrombosis (VLST) at 4 years after the index follow-up angiography in lesions with PSS was significantly higher than that in lesions without PSS (5.3 versus 0.7 %, P \ 0.0001). Late target-lesion revascularization (TLR) was also more frequently observed in the PSS group
M. Imai T. Kimura (&) N. Saito H. Shiomi Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, 54 Shougoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan e-mail: [email protected]
S. Take H. Taniguchi Saiseikai Noe Hospital, Osaka, Japan
T. Morimoto Division of General Medicine, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan
K. Shirota Matsue Red Cross Hospital, Matsue, Japan
R. Kawaguchi H. Kan Gunma Prefectural Cardiovascular Center, Maebashi, Japan H. Mukawa Ogaki Municipal Hospital, Ogaki, Japan H. Fujita Kyoto Second Red Cross Hospital, Kyoto, Japan T. Ishise Maizuru Kyosai Hospital, Kyoto, Japan F. Hayashi K. Nagao Osaka Red Cross Hospital, Osaka, Japan
H. Sakamoto T. Yamane National Cerebral and Cardiovascular Center, Osaka, Japan
H. Tamekiyo Tsuchiya General Hospital, Hiroshima, Japan T. Okamura Yamaguchi University Hospital, Yamaguchi, Japan K. Kishi S. Miyazaki Tokushima Red Cross Hospital, Tokushi
Data Loading...
