Impact of chemotherapy regimen and sequence on the effectiveness of scalp cooling for alopecia prevention
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CLINICAL TRIAL
Impact of chemotherapy regimen and sequence on the effectiveness of scalp cooling for alopecia prevention Cynthia Villarreal‑Garza1 · Fernanda Mesa‑Chavez1 · Ma ria Alejandra Garza‑Ledezma1 · Omar Peña‑Curiel1 · Bertha Alejandra Martinez‑Cannon1 · Mauricio Canavati‑Marcos1 · Servando Cardona‑Huerta1 Received: 24 July 2020 / Accepted: 5 October 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Purpose Scalp cooling (SC) is the most reliable method for the prevention of chemotherapy-induced alopecia. However, it remains unclear if its effectiveness is related to the chemotherapy regimen, sequence, and frequency. This study aims to evaluate SC performance among breast cancer patients who received different chemotherapy regimens. Methods The medical records of all consecutive patients undergoing curative-intent chemotherapy and receiving at least one SC session using the DigniCap® System from 2016–2020 in a private Mexican hospital were retrospectively reviewed. SC effectiveness according to chemotherapy regimen was analyzed using descriptive statistics. Successful alopecia prevention was defined as grade 0–1 alopecia (
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