Improved data acquisition efficiency for respiratory motion correction in coronary MRI

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POSTER PRESENTATION

Open Access

Improved data acquisition efficiency for respiratory motion correction in coronary MRI Mehdi H Moghari1,2*, Sébastien Roujol1,2, Markus Henningsson1,2, Raymond H Chan1,2, Susie Hong1,2, Beth Goddu1,2, Lois A Goepfert1,2, Kraig V Kissinger1,2, Warren J Manning1,2, Reza Nezafat1,2 From 15th Annual SCMR Scientific Sessions Orlando, FL, USA. 2-5 February 2012 Summary To investigate the performance of a novel algorithm for correcting respiratory-induced heart motion for wholeheart coronary MRI. Background A right hemi-diaphragm (RHD) respiratory navigator is commonly used to suppress the respiratory motion of the heart in coronary MRI [1]. Typically, a small 5mm end expiratory gating window (GW) is used to gate data. While this technique successfully suppresses respiratory motion, it prolongs scan time due to navigator efficacies of only 30-50%. Increasing the GW to 15mm would increase the navigator efficiency. In this study, we present a novel respiratory motion correction algorithm which allows increasing the GW to 15mm. Methods Whole-heart coronary MRI with isotropic 1.3mm3 resolution was acquired using partial Fourier and a navigator with 15mm GW on a 1.5T Philips CMR scanner from 10 healthy subjects (4 males; 29 ± 13 yr). The navigator RHD positions were used to sort the acquired k-space segments into 15 separate 1mm bins (based on their displacement). To compensate for the respiratory motion of the heart, all k-space segments acquired in each bin were assigned a 3D translation parameter. The 3D translation parameter was estimated using an iterative gradient descent optimization algorithm to correct the kspace segments such that the sharpness of the image, reconstructed using the corrected k-space segments, is maximized. The variance of the gradient of the image was used as the measure for the image sharpness [2]. 1

Harvard Medical School, Cambridge, MA, USA Full list of author information is available at the end of the article

For comparison, another whole-heart coronary MRI dataset was acquired using the same sequence and a navigator with a 5mm GW.

Results Fig.1 displays multi-planner reformatted images acquired using a 5mm GW (A), a 15mm GW without correction (B) and a 15mm GW with the proposed correction technique (C). There is an improvement between images acquired using 15mm GW with correction. The mean and standard deviation of scan acquisition time and efficiency as well as mean and standard deviation of normalized vessel sharpness of right coronary artery (RCA), left anterior descending (LAD) and left circumflex (LCX) arteries are shown in Table 1. However there is an improvement in the mean of the sharpness of LAD and LCX using the proposed technique compared to the reference, but it is not significantly different. Conclusions We present a novel retrospective RHD motion compensation algorithm for whole-heart coronary MRI that allows for widening GW and reduces scan acquisition time by a factor of 2. Funding NIH. Author details 1 Harvard Medical School, Cambridge, MA, U