Incidence of stroke among Saudi population: a systematic review and meta-analysis
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REVIEW ARTICLE
Incidence of stroke among Saudi population: a systematic review and meta-analysis Bader A. Alqahtani 1 & Aqeel M. Alenazi 1 & Jeffrey C. Hoover 2 & Mohammed M. Alshehri 3 & Mohammed S. Alghamdi 4 & Ahmad M. Osailan 1 & Kamlesh Khunti 5 Received: 7 December 2019 / Accepted: 16 June 2020 # Fondazione Società Italiana di Neurologia 2020
Abstract Background and aims Stroke is a leading cause of death and disability worldwide. However, our knowledge of the incidence of stroke for Saudi Arabian population is not known. Thus, we aimed to determine the pooled annual incidence of stroke in Saudi Arabia. Summary of review We conducted a comprehensive literature search of PubMed, Web of Science, and SCOPUS, without language or publication year limits. Outcomes of interest were stroke incidence rate for both first and recurrent. A total of five studies met the inclusion criteria for this review. The pooled annual incidence of stroke in Saudi Arabia was 0.029% (95% CI: 0.015 to 0.047) equivalent of 29 strokes per 100,000 people annually (95% CI: 15 to 47). Conclusion The findings indicate that there are 29 stroke cases for every 100,000 people annually for individuals residing Saudi Arabia. Our values were lower than those of other high-income countries. Establishing a nationwide stroke registry is warranted for monitoring and improving healthcare services provided to stroke survivors. Keywords Epidemiology . Incidence . Prevalence . Stroke . Systematic review
Introduction Despite the medical and rehabilitation advances, stroke is still a leading cause of mortality and disability worldwide [1]. The World Health Organization defined stroke as “rapidly developing clinical signs of focal (or global) disturbance of cerebral function, lasting more than 24 h or leading to death, with no apparent cause other than that of vascular origin” [2]. Sustaining a stroke imposes a huge financial burden that * Bader A. Alqahtani [email protected] 1
Department of Health and Rehabilitation sciences, Prince Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia
2
Department of Educational Psychology, University of Kansas, Lawrence, USA
3
Department of Physical Therapy and Rehabilitation Sciences, Jazan University, Jizan, Saudi Arabia
4
Department of Physical Therapy, Umm Al-Qura University, Mecca, Saudi Arabia
5
Diabetes Research Center, University of Leicester, Leicester General Hospital, Leicester, UK
impacts individuals as well as the health care system worldwide. The estimated cost of care for stroke survivors in the United States is approximately $34 billion each year and expected to increase [3]. In England, the economic cost of stroke is around £7 billion a year [4]. In Saudi Arabia, there are no available data about the cost of care for stroke survivors; however, cost is likely to be high given that the healthcare services are primarily government-funded. There has been conflicting evidence regarding the incidence of stroke in Saudi Arabia. One study found the incidence of stroke to be 29.8 cases per 100,0
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