Increasing newly diagnosed inflammatory bowel disease and improving prognosis in China: a 30-year retrospective study fr
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RESEARCH ARTICLE
Open Access
Increasing newly diagnosed inflammatory bowel disease and improving prognosis in China: a 30‑year retrospective study from a single centre Hong Lv†, Meng Jin†, Huimin Zhang, Xuanfu Chen, Meixu Wu, Mingyue Guo, Runing Zhou, Zheng Wang, Hong Yang* and Jiaming Qian
Abstract Background: We aimed to characterize the trends of prognosis in ulcerative colitis (UC) and Crohn’s disease (CD) in a Chinese tertiary hospital. Methods: A 30-year retrospective cohort analysis was conducted at Peking Union Medical College Hospital. Consecutive patients newly diagnosed with UC or CD from 1985 to 2014 were included. The primary outcome was in-hospital mortality. The secondary outcomes included surgery and length of stay in hospital. The Pearson correlation coefficient was applied to determine the relationship between time and prognosis. Multivariable logistic regression analysis was performed to determine the risk factors for in-hospital mortality and surgery. Results: In total, 1467 patients were included in this study (898 cases with UC and 569 cases with CD). Annual admissions for UC and CD have increased significantly over the last 30 years (UC, r = 0.918, P
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