Interaction of Nanomaterials with the Immune System

This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs). Many ENMs used in both the consumer and biomedical fields have been reported to elicit adverse immune responses ranging from innate immun

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James C. Bonner Jared M. Brown   Editors

Interaction of Nanomaterials with the Immune System

Molecular and Integrative Toxicology

Series Editors Jamie C. DeWitt, East Carolina University, Greenville, NC, USA Sarah Blossom, College of Medicine, ACRI, Arkansas Children’s Hospital Research Institute, Little Rock, AR, USA

Molecular and Integrative Toxicology presents state-of-the-art toxicology in a useful context. Volumes emphasize the presentation of cellular and molecular information aimed toward the protection of human or animal health or the sustainability of environmental systems. More information about this series at http://www.springer.com/series/8792

James C. Bonner  •  Jared M. Brown Editors

Interaction of Nanomaterials with the Immune System

Editors James C. Bonner Department of Biological Sciences North Carolina State University Raleigh, NC, USA

Jared M. Brown Department of Pharmaceutical Sciences Skaggs School of Pharmacy University of Colorado Anschutz Medical Campus Aurora, CO, USA

ISSN 2168-4219     ISSN 2168-4235 (electronic) Molecular and Integrative Toxicology ISBN 978-3-030-33961-6    ISBN 978-3-030-33962-3 (eBook) https://doi.org/10.1007/978-3-030-33962-3 © Springer Nature Switzerland AG 2020 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Preface

Nanotechnology is manipulation of matter at the atomic scale for a plethora of applications, some of which hold solutions for our most pressing challenges, such as energy and medicine. Despite the enormous potential benefits, there is also the potential danger that the advancement of the nanotechnology industry will bring with it adverse human health effects. One recognized effect is the impact of engineered nanomater