Interventions for Persisting Ductus Arteriosus in the Preterm Infant
Over the past few years a remarkably rapid evolution in the professional level of neonatology and in the survival of immature infants has been witnessed. Persisting ductus arteriosus is common in this population and is associated with impaired longterm ou
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M. Obladen (Editor) P. Koehne (Editor)
Interventions for Persisting Ductus Arteriosus in the Preterm Infant With 51 Figures and 7 Tables
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Prof. Dr. Michael Obladen
Dr. Petra Koehne
Director, Department of Neonatology, Charité Universitätsmedizin Berlin, Campus Virchow/Campus Benjamin Franklin, Augustenburger Platz 1, 13353 Berlin [email protected]
Head Physician, Department of Neonatology, Charité Universitätsmedizin Berlin, Campus Virchow, Augustenburger Platz 1, 13353 Berlin [email protected]
ISBN 3-540-24511-1 Springer Medizin Verlag Heidelberg Cataloging-in-Publication Data applied for A catalog record for this book is available from the Library of Congress. Bibliographic information published by Die Deutsche Bibliothek Die Deutsche Bibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data is available in the Internet at . This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer Medizin Verlag. Violations are liable for prosecution under the German Copyright Law. Springer Medizin Verlag. A member of Springer Science+Business Media springer.de © Springer Medizin Verlag Heidelberg 2005 Printed in The Netherlands The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product liability: The publisher cannot guarantee the accuracy of any information about dosage and application thereof contained in this book. In every individual case the user must check such information by consulting the relevant literature. SPIN 11384281 Cover Design: deblik, Berlin, Germany Typesetting: TypoStudio Tobias Schaedla, Heidelberg, Germany Printed on acid free paper
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Preface »Nature knows in advance that the fetal lung, an organ in development and without movement, does not have the same needs as the mature, breathing lung. Nature has therefore connected the pulmonary artery with the aorta.« This was written by Galen in the second century after Christ , confirmed by Giulio Cesare Aranzio in 1564 and later falsely attributed to Leonardo Botallo who became famous by this error. By connecting the pulmonary artery with the aorta, nature had not foreseen that in Europe most infants born at 25–27 weeks gestation would survive at the beginning of the 21st century. Over the past few years we have witnessed a remarkably rapid evolution in the professional level of neonatology and in the survival
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